Browsing by Author "Dedeoglu, Aylin"

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    Calibration of Quartz Tuning Fork transducer by coulometry for mass sensitive sensor studies
    (2019) Dedeoglu, Aylin; Karadas, Nurgul; Unal, Mehmet Altay; Kocum, Ismail Cengiz; Serdaroglu, Dilek Cokeliler; Ozkan, Sibel Aysil
    Mass-sensitive sensing has one main advantage: mass is one of the most fundamental properties of any analyte. They also require suitable recognition materials to ensure selectivity. Quartz Tuning Forks (QTFs) have been known as common oscillator components due to their stable resonant frequencies. In recent years, QTFs have started to be implemented as transducers into sensor systems which has the potential on resulting mass-sensitive sensors with high reliability. In this study, a developed QTF mass-sensitive sensor system has been utilized for applying calculations and finally formulizing the frequency to mass-load relationship for the standard 32,768 Hz QTF. Coulometric copper deposition method was used for a reliable mass-load that could be calculated consequently from the charge reduction measured through the potentiostat. Frequency changes were calculated through the measurements read on the QTF sensor system described. SEM imaging and SEM-EDX element analysis methods were used to assay and confirm the modification performed on the surface.
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    The Power of Carbon Nanotubes on Sensitive Drug Determination Methods
    (2023) Bakirhan, Nurgul K.; Kaya, S. Irem; Jabbarov, Rasim; Gahramanova, Gulnaz; Abdullayeva, Sevda; Dedeoglu, Aylin; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Ozkan, Sibel A.; 34334078
    Nowadays, carbon nanotubes (CNTs) due to their inorganic conducting, semiconducting, and organic pi-pi stacking properties are becoming innovative materials. CNTs have an adjustable size, large surface area, and other significant chemical properties. Due to their excellent electrical, optical, and mechanical properties, CNTs play an important role in various application fields. In the past decade, many unique intrinsic physical and chemical properties have been intensively explored for pharmaceutical, biological, and biomedical applications. The functionalization of CNTs results in a remarkably reduced cytotoxicity and at the same time increased biocompatibility. The toxicity studies reveal that highly water-soluble and serum stable nanotubes are biocompatible, nontoxic, and potentially useful for biomedical applications. Ultrasensitive drug determination from its dosage form and/or biological samples with carbon nanotubes can be realized after surface modification. The main purpose of this review is to present recent achievements on CNTs which are investigated in electrochemical and chromatographically sensing technologies.