Browsing by Author "Colak, T."
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Item Bioimpedance Analysis Reveals Graft Function in Renal Transplant Recipients(2014) Sezer, S.; Demirci, B.; Guliyev, O.; Colak, T.; Sayin, C.; Haberal, M.; https://orcid.org/0000-0002-7326-8388; https://orcid.org/0000-0002-8372-7840; https://orcid.org/0000-0002-3462-7632; JYQ-2550-2024; AAJ-8554-2021; AAJ-8097-2021Item Comparison of parathyroid scintigraphy findings in pediatric and adult patients with secondary hyperparathyroidism(2022) Aktas, A.; Baskin, E.; Gencoglu, A.; Colak, T.Item Elevated FGF-23 Level Could Predict Progressive Arterial Stiffening and Graft Loss in Kidney Transplant Recipients(2014) Sezer, S.; Bal, Z.; Uyar, M. Erkmen; Guliyev, O.; Erdemir, B.; Colak, T.; Haberal, M.; https://orcid.org/0000-0002-8372-7840; https://orcid.org/0000-0002-3462-7632; AAJ-8554-2021; AAJ-8097-2021Item Evaluation of pre- and post-transplantation parathyroid scintigraphy and ultrasonography findings in patients with persistent hyperparathyroidism after renal transplantation(2022) Aktas, A.; Uslu, N.; Gencoglu, A.; Colak, T.Item Graft Function and Arterial Stiffness: Can Bioimpedance Analysis Be Useful in Renal Transplant Recipients?(2015) Sezer, S.; Demirci, B. Gurlek; Guliyev, O.; Sayin, C. B.; Colak, T.; Acar, F. N. Ozdemir; Haberal, M.; 0000-0002-5682-0943; 0000-0002-8372-7840; 0000-0002-3462-7632; 26036549; AAK-1697-2021; AAJ-8554-2021; AAJ-8097-2021Objective. We aimed to determine the total body water (TBW) by means of bioimpedance analysis (BIA) and to analyze the association of TBW, graft function, and arterial stiffness by means of pulse-wave velocity (PWV) and echocardiographic measurements in renal transplant (RT) recipients. Methods. Eighty-two RT recipients (mean age, 38.7 +/- 11.5 y; 58 male) who were using >= 1 antihypertensive treatment were enrolled in the study. Biochemical parameters, 24-hour urinary protein loss, estimated glomerular filtration rate (eGFR), transthoracic echocardiography, bioimpedance analysis according to systolic blood pressure, TBW, lean tissue index (LTI), extracellular water (ECW), intracellular water (ICW), lean tissue mass (LTM), phase angle (Phi50) levels, and renal resistive index (RRI) were evaluated. Results. TBW and ECVV were significantly correlated with systolic blood pressure. Urinary protein loss, pulmonary artery pressure, frequency of overhydration, systolic blood pressure, TBW, LTI, ECW, ICVV, LTM, and Phi50 values were significantly higher in patients with estimated glomerular filtration rate (eGFR) 15-49 mL/min but similar in patients with eGFR 50-70 mL/min. Conclusions. Hypertensive RT recipients have increased TBW, LTI, ICW, FTI, LTM, and Phi50 values. Graft function is positively correlated with systolic blood pressure and BIA parameters. Therefore, hypertensive RT recipients should be closely followed with the use of BIA for an early diagnosis of loss of graft function.Item Hyperuricemia as a Cardiovascular Risk Factor in Renal Transplant Recipients(2014) Uyar, M. Erkmen; Sezer, S.; Bal, Z.; Guliyev, O.; Colak, T.; Demirci, B. Gurlek; Haberal, M.; https://orcid.org/0000-0002-8372-7840; https://orcid.org/0000-0002-3462-7632; AAZ-5795-2021; AAJ-8554-2021; AAJ-8097-2021Item Non-Dipping Hypertension in Renal Transplant Recipients(2014) Sezer, S.; Uyar, M. Erkmen; Bal, Z.; Guliyev, O.; Sayin, B.; Colak, T.; Haberal, M.; https://orcid.org/0000-0001-8287-6572; https://orcid.org/0000-0002-8372-7840; https://orcid.org/0000-0002-3462-7632; AAZ-5795-2021; J-3707-2015; AAJ-8554-2021; AAJ-8097-2021Item Post-Transplant C-Reactive Protein Predicts Arterial Stiffness and Graft Function in Renal Transplant Recipients(2015) Demirci, B. Gurlek; Sezer, S.; Colak, T.; Sayin, C. B.; Tutal, E.; Haberal, M.; 0000-0002-8372-7840; 0000-0002-3462-7632; 26036547; AAJ-8554-2021; AAJ-8097-2021Background. The aim of this study was to evaluate the renal and cardiovascular outcomes of post-transplant c-reactive protein (CRP) levels. Methods. One hundred fifty renal transplant recipients (113 men; median age, 38.9 10.8 years) were cross-sectionally analyzed. Mean pre-transplant and post-transplant CRP levels were analyzed by the 1st, 3rd, 6th, 12th, and 24th months of transplantation. Patients were divided into 3 groups according to mean post-transplantation CRP levels: group 1 (CRP >20 mg/L and fluctuating levels; n = 34), group 2 (CRP, 6-20 mg/L; n = 40), and group 3 (CRP <6 mg/L; n = 76). Arterial stiffness was measured by means of carotid femoral pulse-wave velocity (PWv) by use of the SphygmoCor system. Results. Patients in group 1 had significantly lower estimated glomerular filtration rate (eGFR) (P = .000) and left ventricular systolic function and higher duration of dialysis before transplantation, pulse-wave velocity (PWv), proteinuria, and left ventricular mass index when compared with the other two groups. In regression analysis, eGFR and PWv were detected as the predictors of post-transplantation CRP levels. Conclusions. Fluctuating and high stable (>20 mg/L) post-transplant CRP levels predict eGFR, proteinuria, left ventricular mass index, and PWv after transplantation. Thus, CRP levels may be a useful marker to anticipate graft survival and cardiovascular morbidity in renal transplant recipients.Item Sagittal Abdominal Diameter as an Anthropometric Measure of Cardiovascular and Graft Loss Risk in Renal Transplant Recipients(2015) Bal, Z.; Uyar, M. E.; Tutal, E.; Guliyev, O.; Colak, T.; Sezer, S.; Haberal, M.; 0000-0002-3462-7632; 0000-0002-8372-7840; 26036544; IAO-2608-2023; AAJ-8097-2021; AAZ-5795-2021; AAJ-8554-2021Background. Sagittal abdominal diameter (SAD) has been presented as a stronger prognostic factor for all-cause and cardiovascular mortality in the general population. The aim of this study was to evaluate the relationship between SAD and its associated parameters in renal transplant recipients. Methods. One hundred eighty-one renal transplant recipients were enrolled in the study. All patients were evaluated according to standard clinical and biochemical parameters. Anthropometric measurements were performed for all patients. Pulse-wave velocity (PWV) was determined from pressure tracing over carotid and femoral arteries with the use of the Sphygmocor system. Results. Patients were divided into 2 groups according to SAD measurements. Group 1 (n = 127) was defined as SAD <24.3 cm, and group 2 (n = 54) was defined as SAD > 24.3 cm. Patients in group 2 had significantly higher triglycerides, C-reactive protein (CRP), uric acid, systolic blood pressure, PWV, and body mass index measurements compared with group 1 (P < .05 for all). In group 2, estimated glomerular filtration rate (eGFR) was significantly lower than group 1 (P = .022). SAD had positive correlation with PWV, systolic and diastolic blood pressure, body mass index, triglycerides, fasting glucose, CRP, and uric acid (P < .05 for all). On stepwise linear regression analyses, proteinuria (P = .005), SAD (P = .001), and CRP (P = .015) independently predicted the degree of percentage change of eGFR. Conclusions. Considering the significant association of visceral fat with inflammation and cardiovascular disease, estimating visceral fat by means of SAD could be a useful tool to stratify cardiovascular risk as well as graft function in renal transplant recipients.Item Sagittal Abdominal Diameter as the Anthropometric Measure of Cardiovascular and Graft Loss Risk in Renal Transplant Recipients.(2014) Bal, Z.; Uyar, M. Erkmen; Guliyev, O.; Sayin, B.; Colak, T.; Sezer, S.; Haberal, M.; https://orcid.org/0000-0001-8287-6572; https://orcid.org/0000-0002-8372-7840; https://orcid.org/0000-0002-7326-8388; https://orcid.org/0000-0002-3462-7632; AAZ-5795-2021; J-3707-2015; AAJ-8554-2021; JYQ-2550-2024; AAJ-8097-2021Item Successful Renal Transplantation, Bone Mineral Densitometry, and Affecting Factors(2015) Canoz, M. B.; Yavuz, D.; Altunoglu, A.; Yavuz, R.; Colak, T.; Haberal, M.; 0000-0002-3462-7632; 0000-0002-4082-6320; 0000-0002-8372-7840; 26293056; AAJ-8097-2021; ABG-9980-2021; AAJ-8554-2021Background. Successful renal transplantation corrects many disorders of bone and mineral metabolism owing to the normalization of serum levels of calcium and phosphorus and restoration of calcitriol production. However, successful transplantation does not guarantee complete resolution of the pre-transplantation osteopathy. Methods. This study evaluated 100 patients who underwent successful renal transplantation. We determined the possible risk factors for osteoporosis among 72 male and 28 female renal transplant patients of mean age 32.3 +/- 10.0 years with 81% of them recipients of living-related grafts. Bone mineral densitometry (BMD) was performed in all patients before and >= 1 year after transplantation. Routine test results and demographic data were recorded. Results. At the time of transplantation 76% of the patients had osteoporosis or osteopeni and only 24% of them had normal BMD in 4 regions (femur neck, lumber, radius, and ultradistal). After transplantation, 70% of them had osteopororosis or osteopeni and 30% were normal. After renal transplantation, BMD scores increased (P > .05) although the diagnosis of the bone disease did not change (P < .05). Only preexisting osteodystrophy and smoking were found to be important risk factors for post-transplantation osteoporosis. Conclusions. After renal transplantation, BMD scores increased whereas the diagnosis of bone disease did not change statistically. We found that medical management of osteopenia/osteoporosis before transplantation and smoking habit are the main factors to prevent post-transplantation osteoporosis. Further long-term studies may be more helpful for evaluating the risk factors of post-transplantation osteoporosis.