Browsing by Author "Colak, Meric Yavuz"

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Attitudes and Behaviors Towards Ethical Dilemmas in Organ Transplantation and Organ Donation
(2022) Colak, Meric Yavuz; Pak, Merve Deniz; Haberal, Mehmet; 0000-0002-0294-6874; 0000-0002-3462-7632; AAA-4360-2021; AAJ-8097-2021
Children with Iron Deficiency Anemia Have a Tendency to Hypercoagulation: An Evaluation by Thromboelastography
(2020) Kilci, Ceren; Olcay, Lale; Ozdemir, Beril; Fettah, Ali; Colak, Meric Yavuz; 0000-0002-5684-0581; 0000-0002-0294-6874; 31852173; AAK-3548-2021; AAA-4360-2021
Comparison of ocular discomfort after three different epithelial debridement techniques for corneal collagen cross-linking in keratoconus treatment
(2021) Alkayid, Hosamadden; Asena, Leyla; Yuce, Aslihan; Colak, Meric Yavuz; Altinors, Dilek Dursun; 34250443
Purpose: To compare the severity and duration of ocular discomfort after three different epithelial debridement techniques for corneal collagen cross-linking in the treatment of keratoconus. Methods: Fifty-five patients (65 eyes) known to have keratoconus were enrolled in this retrospective study. The eyes were divided into three groups based on the technique used for epithelial debridement for corneal collagen cross-linking procedure; excimer laser transepithelial phototherapeutic keratectomy was used in group 1 (18 eyes), alcohol-assisted epithelial removal was used in group 2 (27 eyes), and mechanical epithelial debridement was used in group 3 (20 eyes). Preoperative and postoperative (third month) best-corrected visual acuity (BCVA) using Snellen chart, objective refraction, and keratometry results were recorded. The results of the questionnaire obtained from the patient's medical records were reviewed regarding their subjective evaluation of postoperative symptoms including foreign body sensation, tearing, photophobia, and burning at the end of the first postoperative week. Paired-samples t test was used to compare preoperative and postoperative clinical findings. One-way analysis of variance (ANOVA) was used to analyze the differences between three independent groups. Results: BCVA improved from 0.51 +/- 0.27 to 0.58 +/- 0.21 (p = 0.05). Objective mean spherical and cylindrical refraction decreased from -5.08 +/- 2.78D to -4.46 +/- 2.91D (p = 0.22) and from -3.45 +/- 2.73D to -3.03 +/- 1.97D (p = 0.25). Mean maximum keratometry reading (K-max) decreased from 57.63 +/- 4.73D to 56.13 +/- 4.47D (p = 0.001). The mean score for foreign body sensation was the highest in group 3 (4.50 +/- 0.53) and the lowest in group 1 (2.10 +/- 1.85) (p = 0.01). The mean scores for tearing, photophobia, and burning sensation were comparable in three groups (p = 0.84, p = 0.13, and p = 0.61, respectively). The duration of photophobia was the shortest in group 1 (1.50 +/- 2.37 days), followed by group 3 (2.00 +/- 1.31 days) and group 2 (4.00 +/- 1.83 days) (p = 0.04). Conclusions: The severity and duration of adverse subjective symptoms during the first postoperative week after corneal collagen cross-linking appear to be milder with epithelial debridement using excimer laser transepithelial technique compared with -assisted debridement and mechanical debridement.
Differences in Antibody Responses Between an Inactivated SARS-CoV-2 Vaccine and the BNT162b2 mRNA Vaccine in Solid-Organ Transplant Recipients
(2021) Erol, Cigdem; Yalcin, Tugba Yanik; Sari, Nuran; Bayraktar, Nilufer; Soy, Ebru Ayvazoglu; Colak, Meric Yavuz; Azap, Ozlem; Arslan, Hande; Haberal, Mehmet; 0000-0002-3462-7632; 0000-0002-2535-2534; 0000-0002-0993-9917; 0000-0002-5708-7915; 0000-0001-5996-8639; 0000-0002-3165-4520; 34951350; AAJ-1219-2021; AAC-5566-2019; AAJ-8097-2021; ABG-7034-2021; AAA-4708-2022
Objectives: Vaccination against SARS-CoV-2 may reduce COVID-19 mortality and complications in solidorgan transplant recipients, and we evaluated the associated antibody responses and adverse effects in this high-risk population. Materials and Methods: This prospective observational study (April-June 2021) included 10 liver and 38 kidney transplant recipients who received 2 vaccine doses (Sinovac, n = 31; or BioNTech, n = 17) and 56 healthy adults (Sinovac), all of whom provided 3 blood samples (prevaccination, 4 weeks after first dose, and 4-6 weeks after second dose) for quantitative tests (Abbott Quant assay for immunoglobulin G antibodies against SARS-CoV-2 spike protein). Type I error was alpha = .05 in all statistical analyses (SPSS, version 25). Results: We analyzed demographic data, antibody responses, and adverse events after 2 doses of SARS-CoV-2 vaccine, compared immune responses from solidorgan transplant recipients (median age, 36.5 years) versus healthy patients (median age, 37.5 years), and observed significantly higher seropositivity in healthy versus transplant patients after Sinovac vaccination (100% vs 67.5%; P = .001). However, we observed no significant seropositive differences for Sinovac versus BioNTech second doses in transplant recipients. Median SARS-CoV-2 immunoglobulin G level after second dose was significantly higher in BioNTech (1388.6 AU/mL) versus Sinovac patients (136.6 AU/mL) (P = .012). The seropositivity difference between the 2 vaccines was significant in participants 24 to 44 years old (P = .040). The rate of at least 1 side effect was 82.4% (n = 14) for BioNTech vaccine and 32.3% (n = 10) for Sinovac vaccine, and the difference was statistically significant. The most common side effect was arm pain (significantly higher in BioNTech group). Conclusions: Solid-organ transplant recipients demonstrated inadequate vaccine responses (higher risk of complications and mortality) versus healthy patients. Furthermore, immune responses may differ between vaccines. Therefore, additional vaccine doses and strict control measures remain crucial.
Effects of Attachment Styles, Childhood Traumas, and Alexithymia in Turkish Patients with Epilepsy and Functional Seizures
(2023) Keskin, Ahmet Onur; Altintas, Ebru; Yerdelen, Vahide Deniz; Demir, Bireyluel; Colak, Meric Yavuz; 37844436
Introduction: In this cross-sectional study, we used self-report scales to compare childhood traumas, attachment styles, and alexithymia among patients with functional seizures (FS) to patients with epilepsy and healthy controls. We also investigated risk factors associated with FS.Material and methods: A total of 44 patients with epilepsy, 14 patients with FS, and 25 healthy controls were included. All participants were over the age of 18 and were referred to the Baskent University Adana Epilepsy and Video-EEG Center. The patients underwent neurological examinations, brain MRIs, and video-EEG evaluations. Epileptic seizures were classified based on video EEG. The control group consisted of healthy individuals without neurological or psychiatric illness and a history of epileptic seizures or syncope. Beck Depression Inventory (BDI), Childhood Trauma Questionnaire (CTQ), Adult Attachment Scale (AAS), and Toronto Alexithymia Scale-20 (TAS-20) were applied to all participants.Results: Patients with FS had lower educational levels, higher rates of unemployment and single-marital status. The FS group had higher depression, childhood trauma, and alexithymia scores than the other groups. Furthermore, FS patients had a higher prevalence of avoidant attachment. The alexithymia and childhood trauma scores were both correlated with depression. Through the logistic regression analysis, childhood trauma scores and alexithymia were significant risk factors for FS.Conclusion: The use of video-EEG for diagnosing FS can reduce the risk of misdiagnosis and inappropriate antiepileptic treatment. Psychiatric comorbidities, childhood traumas, and alexithymia are prevalent in patients with FS. Therefore, implementing a multidisciplinary treatment approach that addresses the psychological, medical, and social aspects of FS can significantly improve outcomes.(c) 2023 Elsevier Inc. All rights reserved.
Evaluation of Inappropriate Medication Use and Compliance in Elderly People
(2018) Yilmaz, Fikriye; Colak, Meric Yavuz; 0000-0002-4884-3803; 0000-0002-0294-6874; 29564987; AAZ-4775-2020; AAA-4360-2021
Objective: The aim of this study is to evaluate the potentially inappropriate medication use and medication compliance in elderly patients who buy prescribed drugs from a pharmacy in Ankara. Methods: In this cross-sectional field study, 200 older people who bought prescribed drugs from a pharmacy which is close to several hospitals in Ankara in April 2016 were chosen as random sample. A questionnaire consisting of questions related to socio-demographic characteristics, health status, drug use of elderly and Morisky Green Levine Medication Adherence Scale (MGLS) was used to collect data. The appropriateness of the drugs prescribed for elderly was determined by the pharmacist according to Beers criteria. The data were evaluated by descriptive statistics and Chi-Square test. Results: 57.4% of the 200 elderly patients in the study are women and the mean age is 72.55 +/- 6.34 years; 72.6% of them are below high school. When the medication compliance was examined, 36.3% of them did not comply with the drug treatment according to MGLS. It was determined that having sufficient information about the drug, education level, occupation and polymorbidity affect medication adherence (p < 0.05). When the appropriateness evaluated according to Beers Criteria, 41.7% of the subjects were prescribed potentially inappropriate medications (PIM). According to the analysis, the number of drugs prescribed and the type of the chronic disease have effects on the inappropriate prescription (p < 0.05). Conclusion: According to the study, the prevalence of inappropriate medication use in the elderly is higher than the medication non-adherence.
The Healthcare Industry and Medical Devices in Environmental Sustainability: Medical Device Industry is Going Green
(2018) Colak, Meric Yavuz; Colak, Levent; Gurel, Elif; 0000-0002-0294-6874; 0000-0001-7611-3106; AAA-4360-2021
In the whole world there are several developments in order to make a more sustainable and qualified environment to handle the increase costs of the healthcare services industry. The changes in health sector also affect the medical device sector directly as the medical device sector is the most important key of health sector and that is why the concepts element such as environment, sustainability and green are very important in medical sector. The main purpose of the research is to point out the applications of medical device firms concerning environment and sustainability. The research has been planned and carried out as a cross sectional field work in defined type. The medical device firms running in the city center of Ankara are involved in research population. The research is carried out on 60 medical device firms which accept the research within a months of time. Compared with other sectors, it has been concluded that producing sustainable products in medical sector will be more effective, energy applications will be reducing the treatment costs in healthcare, some medical firms in Turkey are ready for energy efficiency applications and energy efficiency applications will reduce 50% energy costs and will protect 50% the environment according to the medical firm's opinions.
Investigation of HIV/AIDS Knowledge Levels and Approaches to the Disease of Başkent University Faculty of Medicine, Dentistry and Engineering Students
(2023) Sari, Nuran; Bilgic, Suveyda; Aydogan, Doga; Akici, Nur Ilayda; Yavuz, Esma Yagmur; Kuscu, Nur Selin; Ardebili, Yasaman; Colak, Meric Yavuz; Azap, Ozlem Kurt; 0000-0002-3171-8926; 0000-0002-0294-6874; 0009-0000-4043-3765; 0000-0002-3165-4520; AAK-4089-2021; AAA-4360-2021
Introduction: The number of HIV/AIDS patients is increasing in the world and in our country. It is thought that university students play an important role in developing social awareness necessary for the control of infectious diseases. This study aims to investigate the knowledge level of university students, determine their attitudes towards the disease, and evaluate their behavioral patterns to provide guidance for future studies, training and practices.Materials and Methods: Our research is a descriptive, cross-sectional field study. A survey including questions about HIV/AIDS trans- mission routes, disease recognition, attitudes and behaviors was prepared and delivered to the students of our university's faculty of medicine, dentistry and engineering via an online system. The survey data conducted between February 14, 2022 and April 1, 2022 was recorded and analyzed in the SPSS 25 statistical package program.Results: A total of 233 students participated in the survey, 76 from the faculty of engineering, 121 from the faculty of medicine, and 36 from the faculty of dentistry. 159 of the students are women and 73 are men. The average age was found to be 22.8 +/- 1.9 years. Between the students of the faculty of engineering and the group studying in the field of health; There was a significant difference in knowing the HIV/AIDS difference, ways of protection and disease agent (p< 0.05). In addition, questions about the ways of HIV transmission; There is a significant difference between the two groups regarding genetic transmission, use of the same forks and knives, towels, public toilets, kissing, sneezing, shaking hands, and contamination from swimming pools (p< 0.05). Knowledge that it can be transmitted through blood transfusion, using the same razor and needle, getting a tattoo, pregnancy and birth was found to be significantly lower in the faculty of engineering (p< 0.05). Additionally, 14.5% of the faculty of engineering students thought that they could be protected from HIV/AIDS by exercising regularly and 36.8% thought that they were vaccinated against HIV/AIDS (p< 0.05).To the question of whether HIV/AIDS patients pose a threat to society, 33.5% of students studying in the field of health and 34.2% of students of the faculty of engineering answered yes. The rate of those who want to learn more about HIV/AIDS is 86% in the field of health and 80.3% in the faculty of engineering.Conclusion: In our study, it was also observed that although university students had a certain level of knowledge about HIV/AIDS, they had incomplete and wrong attitudes and behaviors. Necessary training on infectious diseases of public concern must cover all departments.
Macular Imaging Characteristics in Children with Myelinated Retinal Nerve Fiber and High Myopia Syndrome
(2023) Sezenoz, Almila Sarigul; Oto, Sibel; Akkoyun, Imren; Bayar, Sezin Akca; Yilmaz, Gursel; Colak, Meric Yavuz; 0000-0003-0171-4200; 0000-0002-2860-7424; 0000-0001-5109-755X; 0000-0002-7030-5454; 0000-0002-0294-6874; 37602641; AAJ-4668-2021; AAK-7713-2021; AAJ-2406-2021; AAJ-4860-2021; AAA-4360-2021
Objectives: To investigate the macular imaging features in patients with unilateral myelinated retinal nerve fiber (MRNF) and high myopia syndrome. Materials and Methods: Six patients with unilateral MRNF and high myopia syndrome and 13 myopic controls were enrolled in this study. Spectral domain (SD) optical coherence tomography (OCT), SD enhanced depth imaging OCT, and OCT angiography (OCTA) imaging results of MRNF-affected eyes were compared with the fellow eyes and myopic controls. Results: All patients had abnormal foveal reflex and/or ectopia. No significant difference in retinal thickness parameters were noted between the groups. In OCT scans, posterior vitreous detachment (PVD) was observed in 4 out of the 6 MRNF-affected eyes. Regarding OCTA parameters, only a significant increase in acircularity index was noted in myelinated eyes (p=0.01). Conclusion: All patients demonstrated normal foveal contours, macular structure, and OCTA features except for a higher acircularity index. The incidence of PVD was notably increased in the myelinated eyes.
A New Era in Transplantation: Artificial Intelligence, Augmented Reality, Virtual Reality and Metaverse
(2022) Colak, Meric Yavuz; Haberal, Mehmet; 0000-0002-0294-6874; 0000-0002-3462-7632; AAA-4360-2021; AAJ-8097-2021
A Retrospective Analysis Of Benign Paediatric Jaw Lesions According To New World Health Organization Classification
(2022) Cubuk, Secil; Colak, Meric Yavuz; 35599042
The aim of this study was to evaluate the benign paediatric jaw lesions based on the 2017 World Health Organization (WHO) classification. Demographic data, symptoms, radiographic findings, location, size, histopathologic diagnosis, treatment modalities, and outcomes were analysed retrospectively. Recurrence incidence, time to recur, and follow-up time were also evaluated. One hundred seven lesions were diagnosed in 100 patients (44 female, 56 male). The mean follow-up time was 56.6 ?? 45.7 months. The mean age was 12.9 ?? 3.9 years and the majority of lesions were found in the permanent dentition group (p = 0.045). There were 73 patients with odontogenic cysts, followed by 16 patients with odontogenic tumors, and 11 patients with non-odontogenic tumors. Eighty seven lesions (81%) were radiolucent and 93 lesions (86%) were well-circumscribed. The majority of the patients (n = 96) were treated by enucleation. Recurrence was seen in 3 patients. The most notable difference between the results of the present study and the results of the study conducted in medical institutions was the distributions of jaw lesions. Within the limitations of the study it seems that a conservative treatment of benign jaw lesions should be preferred in the paediatric population because this treatment yields acceptable results. ?? 2022 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.