Browsing by Author "Chin, L Thomas"

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    Liver Transplantation for Biliary Atresia: 19-Year, Single-Center Experience
    (Başkent Üniversitesi, 2004-06) Chin, L Thomas; D’Alessandro, Anthony M; Knechtle, Stuart J; Fernandez, Luis A; Leverson, Glen; Judd, Robert H; Spaith, Elizabeth; Dalgic, Aydin; Sollinger, Hans W; Kalayoglu, Munci
    In this study, we describe our 19-year experience with liver transplantation as the definitive treatment for congenital biliary atresia. Materials and Methods: We performed a retrospective study of 115 liver transplants from 1984 to 2003 in 85 patients with congenital biliary atresia. We determined the impact of era of transplantation (1984-1993 and 1994-2003), recipient age (< 1 and > 1), prior portoenterostomy, and type of surgery (whole-, reduced-, and split-liver transplant) on the outcome of the transplant. Results: Overall long-term survival is 83%. Survival is greater in the more-recent era. No impact of age or prior portoenterostomy on survival was seen. Split- liver grafts showed superior graft survival, whereas reduced-liver transplants had the worst overall graft survival. Conclusions: Our results confirm that long-term patient survival after liver transplantation for congenital biliary atresia is excellent. When required, partial liver grafts provide excellent long-term outcome.