Browsing by Author "Bulut, Cemal"

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    Association of Clinical Properties and Compatibility of the Quantiferon-TB Gold In-Tube Test with the Tuberculin Skin Test in Patients with Psoriasis
    (2016) Togral, Arzu Karatas; Koryurek, Ozgul Mustu; Sahin, Muzaffer; Bulut, Cemal; Yagci, Server; Eksioglu, Hatice Meral; 26498894; GPX-6417-2022; GRY-5217-2022
    BackgroundIndividuals with psoriasis show conflicting responses to the tuberculin skin test (TST), a commonly used screening test for latent tuberculosis infection. An alternative to TST is QuantiFERON-TB Gold In-Tube test (QFT-GIT), an in vitro interferon-gamma release assay. This study aimed to determine the effect of the clinical properties of psoriasis (disease severity and koebnerization status) on TST results and the agreement between the TST and QFT-GIT results in psoriatic patients. MethodsOne hundred patients with mild to severe psoriasis were enrolled in this prospective cross-sectional study. Psoriasis properties, including disease severity (psoriasis area and severity index score and koebnerization status), latent tuberculosis infection risk factors, and bacillus Calmette-Guerin vaccination history, were recorded. All patients underwent a TST and QFT-GIT. TST positivity cut-off point was 10 mm for bacillus Calmette-Guerin-vaccinated patients and 5 mm for non-vaccinated patients. ResultsPsoriasis area and severity index scores and koebnerization status did not correlate with TST diameters. Only one of the 23 koebnerization-positive patients developed koebnerization in response to TST. QFT-GIT positivity was prominently higher in the TST-positive group, and this was the only factor that differed between the TST-positive and TST-negative groups (P < 0.001). ConclusionTuberculin skin test results were not affected by psoriasis severity or koebnerization status. QFT-GIT positivity was prominently higher in the TST-positive group (P < 0.001). Overall agreement between TST and QFT-GIT results was moderate ( = 0.413). Concurrent negativity (44%) was higher than concurrent positivity (27%).
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    Crimean-Congo Hemorrhagic Fever Presented with Headache: A Case Report
    (2014) Ocal, Ruhsen; Delikan, Okan; Cebi, Kazim; Ocal, Serkan; Bulut, Cemal; Bayazit, Tolga; https://orcid.org/0000-0003-3719-9482; ABH-4817-2020
    Headache is one of the most common symptoms of patients applying to emergency departments. In the majority of these patients the cause is usually primary. Although secondary headaches are less common, the diagnosis of the underlying reasons is important since they may be due to a potentially dangerous cause. Headache is also a common symptom of infection. The first symptom of infection can be a serious headache. Headaches which do not respond to medical treatment usually suggest secondary headache. Crimean-Congo haemorrhagic fever (CCHF) is an endemic disease with high mortality. Timely diagnosis as well as treatment of patients with high rates of transmission is also important in terms of disease prevention measures. In this study, a patient diagnosed as CCHF as a cause of secondary headache has been reported.