Browsing by Author "Bilgin, E."
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Item Disease Characteristics of Psoriatic Arthritis Patients May Differ According to Age at Psoriasis Onset: Cross-Sectional Data from the Psoriatic Arthritis-International Database(2021) Bilgin, E.; Aydin, S. Z.; Tinazzi, I.; Bayindir, O.; Kimyon, G.; Ozisler, C.; Dogru, A.; Dalkilic, E.; Aksu, K.; Cetin, G. Yildirim; Yilmaz, S.; Solmaz, D.; Omma, A.; Can, M.; Kucuksahin, O.; Yavuz, S.; Ersozlu, E.D.; Kilic, L.; Tarhan, E.F.; Tufan, M.A.; Akyol, L.; Cinar, M.; Erden, A.; Gonullu, E.; Yildiz, F.; Bakirci, S.; Erbasan, F.; Esmen, S.Ergulu; Kucuk, A.; Tufan, A.; Balkarali, A.; Mercan, R.; Erten, S.; Akar, S.; Kasifoglu, T.; Duruoz, T.; Yazisiz, V.; Kalyoncu, U.; 32662407Objective To explore the impact of early versus late-onset psoriasis (PsO) on the disease characteristics of psoriatic arthritis (PsA) in a large-multicentre cohort. Methods The data from a multicentre psoriatic arthritis database was analysed. Patients were grouped according to age at psoriasis onset (early onset; 40 years of age, late-onset; 40 years of age) and disease characteristics of the groups were compared by adjusting for BMI and PsA duration, where necessary. Results At the time of analyses, 1634 patients were recruited [62.8% females; early onset 1108 (67.8%); late-onset, 526 (32.2%)]. The late-onset group was more over-weight [66.8% vs. 86.8%, p<0.001; adjusted for age -aOR 1.55 (1.11-2.20; 95% CI)]. The early onset group had more scalp psoriasis at onset (56.7% vs. 43.0%, p<0.001), whereas extremity lesions were more common in the late-onset group (63.8% vs. 74.2%, p<0.001). Axial disease in males and psoriatic disease family history in females were significantly higher in the early onset group [38.0% vs. 25.4%; p=0.005; adjusted for PsA duration -aOR 1.76 (1.19-2.62; 95% CI) / 39.5% vs. 30.1%; p=0.003; OR 1.51 (1.15-1.99; 95% CI), respectively]. Psoriatic disease activity parameters, patient-physician reported outcomes and HAQ-DI scores were similar in both groups. Conclusion Clinical features of PsA may be affected by the age at onset of PsO. Different genetic backgrounds in early and late-onset PsO may be driving the differences in psoriasis and PsA phenotypes.Item Performance of 2022 Acr/Eular Gpa, Egpa and Mpa Classification Criteria in Turkish Vasculitis Study Group Prospective Cohort (TRVAS)(2023) Bolek, E. C.; Ayan, G.; Bilgin, E.; Ediboglu, E. Durak; Duran, E.; Kardas, C.; Yildirim, T. Demirci; Ozdemir, B.; Ogut, T. S.; Karabacak, M.; Cagdas, O. Sadioglu; Yildirim, R.; Erpek, E.; Ozgur, D.; Akleylek, C.; Acar, E. A.; Uludogan, B. C.; Unaldi, E.; Uzun, G. Sandal; Ekici, Z. Ozsoy M.; Firlatan, B.; Kart-Bayram, S.; Kutu, M. E.; Mutlu, M. Yalcin; Armagan, B.; Gercik, O.; Bitik, B.; Kucuk, H.; Yilmaz, N.; Bilge, N. S. Yasar; Celik, S.; Kilic, L.; Kasifoglu, T.; Yazici, A.; Bes, C.; Erden, A.; Erbasan, F.; Asicioglu, E.; Alibaz Oner, F.; Omma, A.; Cefle, A.; Yazisiz, V.; Ozturk, M. A.; Direskeneli, H.; Kiraz, S.; Onen, F.; Akar, S.; Karadag, O.