Browsing by Author "Basaran, Betul"

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    The Effect of Spinal Versus General Anesthesia on İntraocular Pressure in Lumbar Disc Surgery in The Prone Position: A Randomized, Controlled Clinical Trial
    (2018) Pinar, Huseyin Ulas; Kasdogan, Zumrut Ela Arslan; Basaran, Betul; Coven, Ilker; Karaca, Omer; Dogan, Rafi; https://orcid.org/0000-0003-0473-6763; https://orcid.org/0000-0003-1933-2075; 29414618; Q-2420-2015; GQO-9198-2022
    Objective: To compare IOP changes between spinal anesthesia (SA) and general anesthesia (GA) in patients who underwent lumbar disc surgery in the prone position. Design: Prospective, randomized, controlled trial. Setting: Operating room. Patients: Forty ASA I-II patients scheduled for lumbar disc surgery in prone position. Intervention: Patients were randomly allocated to the SA or GA groups. Measurements: IOP was measured before anesthesia (IOP1), 10 min after spinal or general anesthesia in supine position (IOP2), 10 min after being placed in the prone position (IOP3), and at the end of the operation in the prone position (IOP4). Main results: There was no significant difference between baseline IOP1 (group GA = 19.4 +/- 3.2 mmHg; group SA = 18.6 +/- 2.4 mmHg) and IOP2 values (group GA = 19.7 +/- 4.1 mmHg; group SA = 18.4 +/- 1.9 mmHg) between and within the groups. IOP values after prone positioning and group GA measurements (IOP3 = 21.6 +/- 3.1 mmHg; IOP4 = 33.9 +/- 3.1 mmHg) were significantly higher when compared with the SA group (IOP3 = 19.3 +/- 2.7 mmHg, IOP4 = 26.9 +/- 2.4 mmHg) (p = 0.018 and p < 0.001, respectively). Furthermore, IOP3 was significantly increased when compared with IOP2 in the GA group but not in the SA group (p = 0.019 and p = 0.525, respectively). In both groups, IOP4 values were significantly higher than the other three measurements (p < 0.001). Conclusion: The results indicated that IOP increase is significantly less in patients who undergo lumbar disc surgery in the prone position under SA compared with GA.
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    High Prolactin Level as a Predictor of Vasospasm in Aneurysmal Subarachnoidal Hemorrhage
    (2017) Kircelli, Atilla; Coven, Ilker; Duman, Enes; Pinar, Huseyin Ulas; Basaran, Betul; 0000-0003-0473-6763; 0000-0003-2109-1274; 28784938; Q-2420-2015; AAK-5299-2021
    Background: Aneurysmal subarachnoid hemorrhage (aSAH) is a destructive syndrome with a mortality rate of 50%. Recent studies have also suggested a high pervasiveness of hypothalamic-pituitary insufficiency in up to 45% of patients after aSAH. Prolactin has been associated with the pathogenesis of hypertensive irregularities that are linked to pregnancy. Material/Methods: We identified a group of 141 patients with spontaneous SAH due to a ruptured cerebral aneurysm; these patients were operated on at our institution's Neurosurgery and Interventional Radiology Department between 2011 and June 2015. All of the data were obtained retrospectively from medical records. Results: The hormonal abnormalities observed in the initial 24 h after ictus in subjects with subarachnoid SAH were caused by stressful stimulation aggravated by intracranial bleeding. Conclusions: The elevated prolactin levels that occur in patients with aSAH can be used in conjunction with other auxiliary factors that we believe may be beneficial to vasospasm.
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    Tubeless Percutaneous Nephrolithotomy: Spinal versus General Anesthesia
    (2014) Gonen, Murat; Basaran, Betul
    Purpose: Tubeless percutaneous neplarolithotomy (PCNL) with double-J stenting is a good option for large kidney calculi without increasing blood loss. In many centers tubeless PCNL is performed under general anesthesia. In the present study we evaluated the impact of spinal anesthesia in patients undergoing tubeless PCNL. Material and Methods: Between February 2011 and February 2012, forty six patients with kidney calculi were treated with tubeless PCNL. Of these patients 26 were treated under spinal anesthesia (group 1) and remaining 20 were treated under general anesthesia (group 2). Groups were compared according to patient demographics, stone size, access number, operative time, presence of supracostal access, analgesic requirement, length of hospital stay, and complications. Results: There were not any statistically significant differences between groups in terms of patient demographics, mean stone size, mean access number, operative time, presence of supracostal access, and length of hospital stay. However, the analgesic requirement was significantly less in group 1 (53 +/- 39 mg vs. 111 +/- 46 mg, intravenous tramadol in groups 1 and 2, respectively P < .001). Conclusion: Tubeless PCNL under spinal anesthesia is a good alternative for general anesthesia in adult patients. Spinal anesthesia decreases analgesic requirement in patients that were performed tubeless PCNL compared to general anesthesia.