Başkent Üniversitesi Kurumsal Akademik Arşivi
Başkent Üniversitesi DSpace, üniversitemiz tarafından doğrudan veya dolaylı olarak yayınlanan kitap, makale, tez, bildiri, rapor ve araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar. Bu sistem, üniversitemizin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak amacıyla telif haklarına uygun olarak Açık Erişim imkanı sağlar.
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Combination Antifungal Therapy for Invasive Pulmonary Aspergillosis in a Heart Transplant Recipient
(Başkent Üniversitesi, 2011-08) Beiras-Fernandez, Andres; Kaczmarek, Ingo; Reichart, Bruno; Ueberfuhr, Peter; Michel, Sebastian; Nickel, Thomas; Bigdeli, Amir K.
Invasive pulmonary aspergillosis is a severe complication after solid organ transplant, with a high mortality rate. We present a 45-year-old male heart transplant recipient who developed fever, progressive worsening of dyspnea, and productive cough without response to antibiotics. Diagnosis of invasive pulmonary aspergillosis was made based on clinical, laboratory, and radiographic findings. The patient was treated successfully with combined antifungal therapy (voriconazole and micafungin). This case report highlights the importance of a high degree of clinical suspicion to allow curative treatment of invasive aspergillosis and the efficiency of new antifungal drugs.
Bilateral Transversus Abdominis Plane Block for Managing Pain After a Pancreas Transplant
(Başkent Üniversitesi, 2011-08) Aniskevich, Stephen; Torp, Klaus D.; Clendenen, Steven R.
The authors report the first clinical application of a bilateral transversus abdominis plane block for treating pain after a pancreas transplant. In this case, a 36-year-old chronic opioid user presented postoperatively with severe incisional pain following a pancreas transplant. The pain was not ameliorated with opioids and was successfully treated with the administration of bilateral transversus abdominis plane blocks with 0.5% ropivicaine. Pain relief lasted for 6 hours.
Liver Transplantation From an Upper Midline Incision
(Başkent Üniversitesi, 2011-08) Kayaalp, Cuneyt; Yilmaz, Sezai; Aydinli, Bulent; Ozgor, Dincer; Baskiran, Adil; Unal, Bulent; Aydin, Cemalettin
Objectives: To evaluate the minimally invasive incision to the recipient of a liver transplant.
Materials and Methods: A 55-year-old man with cirrhosis due to hepatitis B accompanied by hepatocellular carcinoma underwent a right lobe, living-donor liver transplant using an 18-cm long, upper midline incision. The recipient hepatectomy was performed from the left to the right side (from medial to lateral). Deep retractors and long surgical instruments were preferred.
Results: The surgical procedure was completed without problem. Both the recipient hepatectomy and implantation of the right liver took 8 hours. Postoperative recovery of the patient was rapid, and he was discharged 8 days after surgery, uneventfully.
Conclusions: An upper midline incision can be preferred for liver transplant for selected cases. Minimally invasive surgery is an option for liver transplant recipients as well.
Flupirtine-induced Hepatic Failure Requiring Orthotopic Liver Transplant
(Başkent Üniversitesi, 2011-08) Klein, Fritz; Neuhaus, Peter; Seehofer, Daniel; Rudolph, Birgit; Glanemann, Matthias
We present the case of a 48-year-old otherwise healthy man who required an urgent liver transplant owing to acute liver failure after flupirtine treatment. After 3 months of daily flupirtine intake as treatment for pseudoradicular pain syndrome, he presented at our institution with signs of jaundice and hepatic encephalopathy. Laboratory results showed elevated liver transaminases, and the liver histopathology supported the assumed drug-induced liver injury. After listing him for an urgent liver transplant, he was given a liver graft from a 21-year-old man. Despite a rejection episode on day 11 after the surgery (which was successfully treated by steroid pulse therapy), the postoperative course was uneventful and the patient recovered completely. To the best of our knowledge, this is the first report of a liver transplant for acute liver failure after taking flupirtine.
Aspergillus Fumigatus Spondylodiskitis in Renal Transplant Patient: Voriconazole Experience
(Başkent Üniversitesi, 2011-08) Ersoy, Alparslan; Ener, Beyza; Akalin, Halis; Oruc Koc, Aysegul; Dizdar, Oguzhan Sitki
The incidence of invasive aspergillosis has increased after solid organ transplant. However, aspergillus osteomyelitis in vertebrae is rare. We report a case of aspergillus spondylodiskitis after pulmonary aspergillosis in a renal transplant recipient. He was treated by antifungal therapy and surgical intervention. The transplantist should be alert for a diagnosis of aspergillus spondylodiskitis in recipients who developed back pain after aspergillosis infection in other sites.