Browsing by Author "Efe, Duran"

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    Association of neutrophil/lymphocyte ratio with obstructive coronary artery disease and coronary artery calcium score detected by multislice computed tomography in type 2 diabetes mellitus patients
    (2015) Aygun, Fatih; Efe, Duran; 26229449
    Objective: The aim of the present study was to investigate the association of neutrophil/lymphocyte ratio (NLR) with coronary artery calcium score (CACS) and obstructive coronary artery disease (CAD) detected by multislice computed tomography (MSCT) angiography in type 2 diabetes mellitus (T2DM) patients. Methods: Two hundred and ninety-two T2DM patients, who were either asymptomatic or symptomatic (but noncharacteristic) for coronary artery disease (CAD) and underwent MSCT angiography in our clinic between May 2009 and June 2014, were enrolled. All patients were divided into two groups according to their mean NLR values. Patients with NLR. 2.05 were assigned to Group 1 and patients with NLR. 2.05 were assigned to Group 2. The association of NLR with CACS and obstructive CAD, which were detected by MSCT angiography, was investigated in T2DM patients. Results: According to the Agatston scoring method, the mean CACS was 129.5 +/- 209.8 Au in Group 1 and 290.3 +/- 399.6 Au in Group 2 (P<0.001). Obstructive CAD was detected in 40 (26.8%) patients in Group 1 and in 56 (39.2%) patients in Group 2 (P<0.05, P=0.021). Conclusion: The rate of obstructive CAD was significantly higher in the T2DM patients with NLR. 2.05 than that in the T2DM patients with NLR. 2.05. In addition, the CACS was also significantly higher in the T2DM patients with NLR. 2.05 than that in the T2DM patients with NLR. 2.05.
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    Investigation of Relation Between Visceral and Subcutaneous Abdominal Fat Volumes and Calcified Aortic Plaques Via Multislice Computed Tomography
    (2015) Efe, Duran; Aygun, Fatih; Acar, Turker; Yildiz, Melda; Gemici, Kazim; 0000-0002-9060-2691; 25245049; P-7416-2014; P-5653-2014
    Objective: The present study investigated effect of subcutaneous fat volume and abdominal visceral fat volume on aortic atherosclerosis via multislice computed tomography. Materials and methods: The present study comprised 424 subjects who underwent non-contrast-enhanced abdominal CT in our clinic between June 2012 and June 2013. Using dedicated software visceral fat volume was calculated for each individual and then subcutaneous fat volume was calculated by subtracting visceral fat volume from total fat volume. By dividing visceral fat volume/subcutaneous fat volume participants were assigned to three groups according to their mean visceral fat volume/subcutaneous fat volume: Group 1 consisted of subjects with visceral fat volume/subcutaneous fat volume lower than 0.48 (Group 1< 0.48); Group 2 consisted of subjects with visceral fat volume/subcutaneous fat volume equal to or higher than 0.48 and lower than 0.69 (0.48 <= Group 2< 0.69); and Group 3 consisted of subjects with visceral fat volume/subcutaneous fat volume equal to or higher than 0.69 (Group 3 >= 0.69). Results: The mean abdominal aortic calcium scores according to Agatston scoring (au) were 136.8 +/- 418.7 au in Group 1, 179.9 +/- 463 au in Group 2 and 212.2 +/- 486.9 in Group 3, respectively. Conclusions: We have demonstrated a significant correlation between visceral fat volume and abdominal aorta atherosclerosis, while there was absence of significant correlation between subcutaneous fat volume and abdominal atherosclerosis.