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Comparative in Vitro Activities of Omadacycline, Eravacycline and Tigecycline Against Non-ESBL- Producing ESBL- Producing and Carbapenem- Resistant Isolates of K. Pneumoniae
Mirza, Hasan Cenk; Guclu, Aylin Uskudar; Ceviz, Gizem Ince; Basustaoglu, Ahmet (2022)Introduction. Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae and carbapenem-resistant Enterobacte-riaceae are characterized by the World Health Organization as pathogens for which new antibiotics are ... -
Comparison of in vitro activities of plazomicin and other aminoglycosides against clinical isolates of Klebsiella pneumoniae and Escherichia coli
Ince, Gizem; Mirza, Hasan Cenk; Guclu, Aylin Uskudar; Gumus, Hale; Erol, Cigdem; Basustaoglu, Ahmet (2021)Objectives: To compare the in vitro activity of plazomicin and two older aminoglycosides (gentamicin and amikacin) against 180 isolates of Escherichia coli and Klebsiella pneumoniae, including subsets of 60 non-ESBL-producing, ... -
Evaluation of a Commercial Broth Microdilution Panel for Colistin Susceptibility Testing of Clinical Isolates of Escherichia coli and Klebsiella pneumoniae
Mirza, Hasan C.; Bicakcigil, Asiye; Liste, Umran; Sancak, Banu (2021)Background: Colistin is among the last resort antibiotics for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. Antimicrobial susceptibility testing of colistin is challenging due to its ... -
In vitro activity of ceftolozane-tazobactam and ceftazidime-avibactam against clinical isolates of meropenem-non-susceptible Pseudomonas aeruginosa: A two-centre study
Mirza, Hasan Cenk; Hortac, Elvan; Kocak, Aylin Altay; Demirkaya, M. Hamiyet; Yayla, Buket; Guclu, Aylin Uskudar; Bustaoglu, Ahmet (2020)Objectives: This study aimed to compare the activity of ceftazidime-avibactam (C/A), ceftolozane-tazobactam (C/T) and three anti-pseudomonal beta-lactams (piperacillin-tazobactam, ceftazidime and cefepime) against a ... -
In vitro Activity of Delafloxacin against Methicillin-Resistant Staphylococcus aureus Isolated from Various Clinical Specimens
Mirza, Hasan Cenk; Basustaoglu, Ahmet; Yanik Yalcin, Tugba (2021)Introduction: Delafloxacin is a novel fluoroquinolone which has anionic and weak acid character at neutral pH. Activity of delafloxacin is reported to be increased in acidic environments. Many infections are characterized ... -
Investigation of anti-cholinesterase and anti-amyloidogenic activities of beta-lactam antibiotics
Ozer, Eda Ozturan; Mirza, Hasan Cenk; Tan, Oya Unsal; Turkoglu, Suna (2022)Objectives: Neuroinflammation is an important factor in the pathogenesis of neurodegenerative disesases. The following study aimed to clarify the effects of beta-lactam antibiotics to the cholinergic system, on ... -
Prevention of Candida biofilm formation over polystyrene by plasma polymerization technique
Kaleli-Can, Gizem; Hortac-Istar, Elvan; Ozguzar, Hatice Ferda; Mutlu, Mehmet; Mirza, Hasan Cenk; Basustaoglu, Ahmet; Gocmen, Julide Sedef (2020)This work investigates the antifungal effect of plasma polymer films produced by low-pressure RF-generated plasma system using acrylic acid, 2-hydroxyethyl methacrylate, and diethyl phosphite (DEP). Unmodified and ...