Prevention of Candida biofilm formation over polystyrene by plasma polymerization technique
Tarih
2020Yazar
Kaleli-Can, Gizem
Hortac-Istar, Elvan
Ozguzar, Hatice Ferda
Mutlu, Mehmet
Mirza, Hasan Cenk
Basustaoglu, Ahmet
Gocmen, Julide Sedef
Üst veri
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This work investigates the antifungal effect of plasma polymer films produced by low-pressure RF-generated plasma system using acrylic acid, 2-hydroxyethyl methacrylate, and diethyl phosphite (DEP). Unmodified and plasma-modified polystyrene (PS) microplate wells were tested by 30 biofilm-positive Candida spp. isolated from blood samples and two control strains using a quantitative plaque assay method. Regardless of the precursors and plasma parameters, biofilm formation was inhibited for all plasma-modified microplate wells. The most significant anti-biofilm effect was observed on PS modified by DEP at 90 W plasma power with the inhibition of all Candida species' biofilm formation.