Tuncali, BahattinKirkayak, Ayse Gul TemizkanZeyneloglu, Pinar2022-08-232022-08-2320211306-696Xhttp://hdl.handle.net/11727/7390Lactic acidosis is the most important and life-threatening side effect of metformin that is widely used in the treatment of type 2 diabetes mellitus. In this case report, two cases who were treated in our intensive care unit for lactic acidosis due to high-dose metformin intake for suicidal purposes are presented. The first patient could be successfully treated with continuous venous-venous hemodiafiltration (CVVHDF) and supportive therapy. The second case required endotracheal intubation and mechanical ventilation in addition to CVVHDF and supportive therapy due to delay in treatment.enginfo:eu-repo/semantics/closedAccessContinuous veno-venous hemodiafiltrationlactic acidosismetformin poisoningArticle2755955990006923235000172-s2.0-85115399475