Osken, AltugAkdeniz, EvliyaKeskin, MuhammedOz, AhmetIpek, GokturkZehir, RegayipBarutca, HakanCam, NeseSahin, Sinan2022-09-082022-09-0820210003-3197https://journals.sagepub.com/doi/pdf/10.1177/00033197211014684http://hdl.handle.net/11727/7616This study evaluated the impact of the baseline estimated glomerular filtration rate (eGFR) on clinical and angiographic outcomes and long-term in-stent restenosis (ISR) rates in patients undergoing elective carotid artery stenting (CAS) procedures. Consecutive patients who underwent CAS were retrospectively enrolled (n = 456). At the end of 3 years of follow-up, patients who had died or were lost follow-up were excluded from the study and a final analysis was performed using data from the remaining 405 patients. The study population (n = 405) was divided into 3 tertiles based on the tertile values of the eGFR level (T1, T2, and T3); then, clinical and procedural characteristics and 3-year ISR rates were compared between the groups. An ISR of 50% was detected in 49 (12%) surviving patients. The 3-year ISR was higher among patients with the lowest eGFR values (T1) by 3.7 times (95% CI: 2.01-11.38) than that among patients with the highest eGFR values (T3). These significant relationships persisted following adjustment for confounders. A lower baseline eGFR level was significantly associated with an increased ISR rate. Decreased renal function may be a predictor of ISR after CAS using first-generation stents.enginfo:eu-repo/semantics/closedAccesscarotid artery stentingcarotid interventionglomerular filtration ratein-stent restenosisrestenosisarticle7287627690006545614000012-s2.0-85105706108