Ergonul, O.Aydin, M.Azap, A.Basaran, S.Tekin, S.Kaya, S.Gulsun, S.Yoruk, G.Kursun, E.Yesilkaya, A.Simsek, F.Yilmaz, E.Bilgin, H.Hatipoglu, C.Cabadak, H.Tezer, Y.Togan, T.Karaoglan, I.Inan, A.Engin, A.Aliskan, H. E.Yavuz, S. S.Erdinc, S.Mulazimoglu, L.Azap, O.Can, F.Akalin, H.Timurkaynak, F.2023-06-162023-06-1620160195-6701http://hdl.handle.net/11727/9632This article describes the prevalence of antibiotic resistance and predictors of mortality for healthcare-associated (HA) Gram-negative bloodstream infections (GN-BSI). In total, 831 cases of HA GN-BSI from 17 intensive care units in different centres in Turkey were included; the all-cause mortality rate was 44%. Carbapenem resistance in Klebsiella pneumoniae was 38%, and the colistin resistance rate was 6%. Multi-variate analysis showed that age > 70 years [odds ratio (OR) 2, 95% confidence interval (CI) 1.22-3.51], central venous catheter use (OR 2.1, 95% CI 1.09-4.07), ventilator- associated pneumonia (OR 1.9, 95% CI 1.1-3.16), carbapenem resistance (OR 1.8, 95% CI 1.11-2.95) and APACHE II score (OR 1.1, 95% CI 1.07-1.13) were significantly associated with mortality. (C) 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.enginfo:eu-repo/semantics/closedAccessBloodstreamGram-negativeHealthcarearticle9443813850003892337000142-s2.0-84996899090