Cok, TayfunKalayci, HakanOzdemir, HalisHaydardedeoglu, BulentParlakgumus, Ayse H.Tarim, Ebru2024-02-152024-02-1520151341-8076http://hdl.handle.net/11727/11543Cesarean scar pregnancy (CSP) is a rare type of ectopic pregnancy, which occurs in previous cesarean section scar tissue, with an incidence of 1 in 1800-3000 pregnancies. Transvaginal ultrasound-guided local methotrexate (MTX) administration presents as a non-systemic option with possible better penetration to the pregnancy site. We present the management of 18 patients with CSP solely by transvaginal ultrasound-guided local MTX administration. All patients were treated with local MTX with a dose of 50mg/m(2). Eleven (61.1%) of the patients did not need any further intervention. Four patients (22.2%) were treated with additional single-dose systemic MTX due to inadequate alteration in blood -human chorionic gonadotrophin levels. Three patients (16.7%) required hysteroscopy and/or laparotomy. We suggest that transvaginal ultrasound-guided local MTX treatment may be considered as a first-line treatment for CSP.enginfo:eu-repo/semantics/closedAccesscesarean scar pregnancyectopic pregnancylocalmethotrexateultrasound-guidedarticle4158038080003539891000232-s2.0-849285911931447-0756