Yildiz, YesimOzger, Hasan SelcukAcar, AliSeremet-Keskin, AysegulBinay, Umut DevrimUnlu, GultenBayram, HalimAsan, AliAkca, Mustafa OzgurKaramanlioglu, DilekInan, OsmanKaya, SafakYildirim, CigdemArslan, YusufKomur, SuheylaSaygideger, YaseminKandemir, Fatma OzlemYasar, SimgeAkdemir-Kalkan, IremTekin-Tas, ZeynepSakiz, AyseBayindir, YasarOzer, Ayse BelinMete, Ayse OzlemErol, CigdemMermutluoglu, CigdemKadiroglu, Ali KemalAzap, AlpaySenol, Esin2024-03-292024-03-2920232667-646Xhttps://www.idcmjournal.org/wp-content/uploads/2023/06/IDCM-2023-216.pdfhttp://hdl.handle.net/11727/11972Objective: We aimed to investigate the vaccination status and the risk factors for the intensive care unit (ICU) support need of the laboratory -confirmed breakthrough COVID-19 infection inpatients. Materials and Methods: This multi -center point -prevalence study was conducted on inpatients, divided into two groups as 'fully' and 'partially' vaccinated according to COVID-19 vaccination status. Results: Totally 516 patients were included in the study. The median age was 65 (55-77), and 53.5% (n=276) of the patients were male. Hypertension (41.9%, n=216), diabetes mellitus (DM) (31.8%, n=164), and coronary artery disease (CAD) (16.3%, n=84) were the predominant comorbidities. Patients were divided into two groups ICU (n=196) and non -ICU (n=301). Hypertension (p=0.026), DM (p=0.048), and congestive heart failure (CHF) (p=0.005) were significantly higher in ICU patients and the median age was younger among non -ICU patients (p=0.033). Of patients, 16.9% (n=87) were fully vaccinated, and this group's need for ICU support was statistically significantly lower (p=0.021). Conclusion: We conclude that older age, hypertension, DM, CHF, and being partially vaccinated were associated with the need for ICU support. Therefore, all countries should continuously monitor post -vaccination breakthrough COVID-19 infections to determine the national booster vaccine administration approach that will provide vulnerable individuals the highest protection. Corresponding Yesim ysmyldz6@gmail.com Accepted: Suggested Yildiz Seremet-Keskin Study Society andenginfo:eu-repo/semantics/openAccessCOVID-19 vaccineintensive care unitrisk factorSARS-CoV-2 infectionvaccine breakthrough infectionsvariant of concernsArticle52118126001162999200001