Erhamamci, S.Reyhan, M.Altinkaya, N.2023-12-292023-12-2920142253-654Xhttp://hdl.handle.net/11727/11258Brain metastases are unusual from urethelial carcinoma of bladder and particularly the occurrence of leptomeningeal metastases is extremely rare, with few cases described in the literature. We present a case of a 45-year-old man with a rare brain metastases as the first metastatic manifestation secondary to urethelial carcinoma of bladder followed by leptomeningeal metastases without any other organ involvement. Eleven months after the diagnosis of high-grade urethelial carcinoma of bladder (T2N0M0), the patient was detected having brain metastases by MRI. FDG PET/CT images for the metastatic evaluation showed no abnormal FDG uptake elsewhere in the body except the brain. Histopathology examination from brain lesion demonstrated the cerebral lesion to be a metastatic urothelial carcinoma. Two months later, the patient was diagnosed to have leptomeningeal metastases by MRI. Our patient's condition gradually worsened, and he died 3 months after the diagnosis of leptomeningeal metastases. (C) 2013 Elsevier Espana, S.L.U. and SEMNIM. All rights reserved.enginfo:eu-repo/semantics/closedAccessUrothelial bladder carcinomaBrain metastasesLeptomeningeal metastasesFDGPET/CTArticle3352902920003418048000072-s2.0-85027947010