Adawy, Nermine M.Helmy, AmrAbdeldayem, Hesham M.Allam, Naglaa A.Salah, EssamAziz, Amr MostafaKashkoush, SamyGad, Hisham2025-11-282009-03Experimental and Clinical Transplantation, Cilt, 7, Sayı, 1, 2009 ss. 18-241304-0855https://hdl.handle.net/11727/14013Objectives: Since brain-death criteria are not accepted in Egypt, only organs acquired from living donors can be used for transplant. Our objective was to highlight the ethical issues raised by living-donor liver transplant. Materials and Methods: The study was conducted by reviewing publications from centers performing living-donor liver transplant in Egypt and by consulting with a group of experts in the fields of liver transplantation, clinical ethics, and religious scholarship. Results: The first successful living-donor liver transplant in Egypt was performed at the National Liver Institute in 1991; however, this program did not continue because of poor early results. In August 2002, transplants began at Dar-Al-Foaud Hospital; since then, almost 500 cases of living-donor liver transplant have been performed at 9 centers. Although the donor risk is estimated to be low, 2 donors died (0.4%). The ethical principle that best applies to living-donor liver transplant is primum non nocere (first, not to harm), as the donor derives emotional benefit from donation and the opportunity to save a life. It is important to stress that the alternative to living-donor liver transplant in Egypt is not deceased-donor liver transplant. There are no doubts that this is a beneficial procedure for the recipient with acceptable risks to the donor. Conclusions: It is ethically appropriate to perform liver transplant using living donors.en-USDonorRecipientAutonomyInformed consentVoluntarismArticle712146-8427