Aygun, DursunDere, Umit AkinYildiz, OnurTemel, YasinKocabicak, Ersoy2020-12-292020-12-2920191019-5149http://turkishneurosurgery.org.tr/pdf/pdf_JTN_2178.pdfhttp://hdl.handle.net/11727/5294AIM: To investigate microelectrode recording (MER)-induced microlesion effect (MLE) on the motor symptoms of 30 patients with Parkinson's disease (PD) who underwent deep brain stimulation of the subthalamic nucleus. MATERIAL and METHODS: MER-induced MLE was evaluated based on the difference between tremor, rigidity, and bradykinesia scores in the preoperative off-state and intraoperative state following MER and before test stimulation. RESULTS: MLE scores improved by 21.7% [left (L) side] and by 13.6% [right (R) side] from baseline (p<0.05). Tremor scores improved by 31.5% (L) and by 14.2% (R) (p<0.05), rigidity scores improved by 17.3% (L) and by 14.2% (R) (p<0.05) and bradykinesia scores improved by 20.6% (L) and by 11.5% (R) (p<0.05) from baseline. There was no significant difference between MLE and the number of microelectrodes used (p> 0.05). CONCLUSION: MER-induced MLE improved motor symptoms and was not correlated with the number of microelectrodes used during the procedure.enginfo:eu-repo/semantics/openAccessParkinson's diseaseSubthalamic nucleusDeep brain stimulationMicroelectrode recordingMicrolesion effectarticle2934304330004669839000182-s2.0-85065868184