Corapcioglu, M. ErdemOgul, Hasan2024-01-292024-01-2920150303-2647http://hdl.handle.net/11727/11351We introduce a novel web-based tool, miSEA, for evaluating the enrichment of relevant microRNA sets from microarray and miRNA-Seq experiments on paired samples, e.g. control vs. treatment. In addition to a group of previously annotated microRNA sets embedded in the system, this tool enables users to import new microRNA sets obtained from their own research. miSEA allows users to select from a large variety of microRNA grouping categories, such as family classification, disease association, common regulation, and genome coordinates, based on their requirements. miSEA therefore provides a knowledge-driven representation scheme for microRNA experiments. The usability of this platform was discerned with a cancer type-classification task performed on a set of real microRNA expression profiling experiments. The miSEA web server is available at http://www.baskent.edu.tr/similar to hogul/misea (C) 2015 Elsevier Ireland Ltd. All rights reserved.enginfo:eu-repo/semantics/closedAccessmicroRNA expression profilingGene set analysisMicroarray analysismiRNA-Seq data analysisarticle13437420003591710000042-s2.0-849349860221872-8324