Kircelli, AtillaCoven, IlkerDuman, EnesPinar, Huseyin UlasBasaran, Betul2019-06-112019-06-1120171643-3750http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5560194&blobtype=pdfhttp://hdl.handle.net/11727/3454Background: Aneurysmal subarachnoid hemorrhage (aSAH) is a destructive syndrome with a mortality rate of 50%. Recent studies have also suggested a high pervasiveness of hypothalamic-pituitary insufficiency in up to 45% of patients after aSAH. Prolactin has been associated with the pathogenesis of hypertensive irregularities that are linked to pregnancy. Material/Methods: We identified a group of 141 patients with spontaneous SAH due to a ruptured cerebral aneurysm; these patients were operated on at our institution's Neurosurgery and Interventional Radiology Department between 2011 and June 2015. All of the data were obtained retrospectively from medical records. Results: The hormonal abnormalities observed in the initial 24 h after ictus in subjects with subarachnoid SAH were caused by stressful stimulation aggravated by intracranial bleeding. Conclusions: The elevated prolactin levels that occur in patients with aSAH can be used in conjunction with other auxiliary factors that we believe may be beneficial to vasospasm.enginfo:eu-repo/semantics/openAccessProlactinSubarachnoid HemorrhageVasospasmIntracranialarticle23383138360004070169000012-s2.0-85029493086