Gurbuz, Ali SamiGode, FundaUzman, Mehmet SukruInce, BetulKaya, MelekOzcimen, NecatiOzcimen, Emel EbruAcar, Ali2019-09-172019-09-1720161757-2215https://ovarianresearch.biomedcentral.com/track/pdf/10.1186/s13048-016-0229-8http://hdl.handle.net/11727/3913Background: To evaluate the effects of an ovulation triggering agent, human chorionic gonadotropin (hCG), versus a gonadotropin-releasing hormone agonist (GnRHa) on early embryo development in vitro using a time-lapse system. Methods: Retrospective analysis of a prospectively collected database. A total of 739 embryos from 152 infertile couples undergoing intracytoplasmic sperm injection cycles. Interventions : Embryo culture in a time-lapse incubator (EmbryoScope, Vitrolife, Goteborg, Sweden). Main Outcome Measures: Embryo morphokinetic parameters. Results: In the 152 women, 252 embryos were derived from GnRHa-triggered cycles compared with 487 embryos derived from hCG-triggered cycles. Time-lapse analysis revealed that embryos from cycles triggered by a GnRHa cleaved faster than embryos derived from hCG-triggered cycles. Conclusion: Triggering with a GnRHa in in vitro fertilization cycles affects embryo kinetics.enginfo:eu-repo/semantics/openAccessAgonist triggerOocyteEmbryo qualityTime lapseMorphokineticarticle90003736726000012-s2.0-84964056061