Durdu, MuratBozca, CansuKocer, Nazim Emrah2019-06-012019-06-0120171307-7635http://cms.galenos.com.tr/Uploads/Article_16147/131-138.pdfhttp://hdl.handle.net/11727/3374A gradual increasing interest in cosmetic procedures and the implementation of these practices by non-physicians have led to the development of various complications. Some of these complications are transient, while others require severe systemic treatments, and some may be life-threatening. These complications cause depression and isolated from society. In this article, three different reactions in the light of literature data due to the application of vitamins E, which are not fillers, have been presented and reactions of filler substances and treatment approaches are reviewed.enginfo:eu-repo/semantics/openAccessFiller reactionsReviewVitamin EScleredemaParaffinomaLipogranulomaarticle1131311380004173495000082-s2.0-85028359555