Turk, EminKaragulle, ErdalCoban, GokcenYildirim, ErkanMoray, Gokhan2019-12-232019-12-2320140020-8868https://www.internationalsurgery.org/doi/pdf/10.9738/INTSURG-D-13-00199.1http://hdl.handle.net/11727/4535We sought to investigate whether application of topical tetracycline has a limiting effect on seroma formation in patients undergoing hernia repair using a polypropylene mesh. This study was conducted in 96 patients undergoing an elective groin hernia repair. Patients were randomized and divided into 2 groups. After the graft was placed, and before external oblique muscle aponeurosis was closed, 5 mL tetracycline was administered on the graft in the tetracycline group (tetra group, n = 50), and 5 mL isotonic saline was administered in the control group (n = 46) without putting in a drain. Seroma checks via surface ultrasonography were done. Seroma amounts measured on the first day were significantly higher in the tetra group (P = 0.04). There were no significant differences regarding seroma measurements on the seventh day or in the first and second months. Topical tetracycline application has no limiting effect on seroma formation after a groin hernia operation.enginfo:eu-repo/semantics/openAccessLichtenstein techniquePolypropylene meshTopical tetracyclineSeromaUltrasonographyarticle992147152000334093700010