Belgin, Huseyin BerkayKale, EdizOzcelik, Tuncer BurakYilmaz, Burak2022-08-052022-08-0520211618-1247http://hdl.handle.net/11727/7239Whether cone beam computed tomography (CBCT) scans can be used for the fabrication of computer-aided design and computer-aided manufacturing (CAD-CAM) fixed dental prostheses (FDPs) is not known. The purpose of the present study was to compare the marginal fit of 3-unit zirconia FDPs fabricated by using CBCT or 3-dimensional (3D) laboratory scanning. Extracted second premolar and molar teeth in a maxillary typodont model were prepared. The first molar was removed and the typodont model was scanned with a laboratory or a CBCT scanner to generate two virtual 3D cast groups (3DL and CBCT). Forty four 3-unit zirconia FDPs were designed on virtual casts and milled. The vertical marginal discrepancy (VMD) was measured by x100-magnification microscopy at seven locations on each abutment. A total of 616 measurements were made at 14 fixed locations in two groups of 22 specimens. The VMD data for 3DL and CBCT groups were statistically analyzed using the Mann-Whitney U test (alpha = 0.05). The mean VMDs on premolar ranged between 44 and 55 mu m (median: 43-55 mu m) in 3DL, and 74 and 100 mu m (median: 72-93 mu m) in CBCT; and on the molar, between 47 and 114 mu m (median: 46-114 mu m) in 3DL, and 91 and 162 mu m (median: 93-156 mu m) in CBCT. There was a significant difference between the gaps in 3DL and CBCT groups (p < 0.001). FDPs fabricated using 3D laboratory scanner had significantly smaller VMDs. Nevertheless, the 3-unit zirconia FDPs fabricated using CBCT scans presented promising marginal integrity.enginfo:eu-repo/semantics/closedAccessMarginal fitZirconiaCAD-CAMCBCTarticle11023393480007087863000022-s2.0-85117178403