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dc.contributor.authorKeskin, Gul Sema
dc.contributor.authorHelvaci, Ozant
dc.contributor.authorYayla, Cagri
dc.contributor.authorPasaoglu, Ozge T.
dc.contributor.authorKeskin, Caglar
dc.contributor.authorArinsoy, Turgay
dc.contributor.authorDeric, Ulver B.
dc.date.accessioned2021-02-28T14:36:02Z
dc.date.available2021-02-28T14:36:02Z
dc.date.issued2019
dc.identifier.issn1300-0144en_US
dc.identifier.urihttps://journals.tubitak.gov.tr/medical/issues/sag-19-49-1/sag-49-1-21-1804-169.pdf
dc.identifier.urihttp://hdl.handle.net/11727/5445
dc.description.abstractBackground/aim: We aimed to evaluate the relationship between YKL-40 and endothelial dysfunction in chronic kidney disease. Materials and methods: Twenty-nine hemodialysis patients, 101 patients with nondialytic (stage 2, 3, 4, and 5 ND) chronic kidney disease (CKD), and 38 healthy individuals as a control group were included. YKL-40 levels were measured by ELISA. Endothelial dysfunction was indirectly measured by flow-mediated dilatation percentage (FMD) in the brachial artery. Results: YKL-40 levels were higher in CKD patients than controls and highest in HD patients (P = 0.001). FMD values were lower in nondialytic CKD patients and lowest in HD patients (P = 0.001). YKL-40 negatively correlated with eGFR and FMD values (r = -0.674 and r = -0.471, respectively). Conclusion: This study shows that YKL-40 increases with CKD stage and is negatively correlated with FMD measurements.en_US
dc.language.isoengen_US
dc.relation.isversionof10.3906/sag-1804-169en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectYKL-40en_US
dc.subjectCKDen_US
dc.subjecthemodialysisen_US
dc.subjectatherosclerosisen_US
dc.subjectendothelial dysfunctionen_US
dc.titleRelationship between plasma YKL-40 levels and endothelial dysfunction in chronic kidney diseaseen_US
dc.typearticleen_US
dc.relation.journalTURKISH JOURNAL OF MEDICAL SCIENCESen_US
dc.identifier.volume49en_US
dc.identifier.issue1en_US
dc.identifier.startpage139en_US
dc.identifier.endpage146en_US
dc.identifier.wos000458367000020en_US
dc.identifier.scopus2-s2.0-85061564678en_US
dc.contributor.pubmedID30763987en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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