Neonatal cerebral sinovenous thrombosis: Two cases, two different gene polymorphisms and risk factors
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Tarih
2017Yazar
Turan, Ozden
Anuk-Ince, Deniz
Olcay, Lale
Sezer, Taner
Gulleroglu, Kaan
Yilmaz-Celik, Zerrin
Ecevit, Ayse
Üst veri
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Cerebral sinovenous thrombosis (CSVT) is a rare disease in the neonatal period and also the greatest risk of neonatal mortality and morbidity. In this report, we presented two cases with CSVT and different risk factors. One of these cases had methylenetetrahydrofolate reductase (MTHFR) C677T homozygous polymorphism and the other case had both MTHFR A1298C homozygous polymorphism, plasminogen activator inhibitor-1 (PAI-1) 4G/5G polymorphism and elevated lipoprotein a. Early diagnosis and prompt initiation of therapy of neonatal CSVT may prevent neonatal mortality and poor long-term neurodevelopmental outcomes.
Bağlantı
http://www.turkishjournalpediatrics.org/uploads/pdf_TJP_1681.pdfhttp://hdl.handle.net/11727/3344