Clinical Characteristics and Outcomes of Nosocomial COVID-19 in Turkey: A Retrospective Multicenter Study
Tarih
2023Yazar
Yildirim, Suleyman
Yilmaz, Celalettin
Polat, Gulru
Baris, Serap
Basyigit, Ilknur
Kaya, Ilknur
Anar, Ceyda
Bozkurt, Mihriban
Baykal, Husnu
Dirol, Hulya
Ozbey, Gamzenur
Ozsari, Emine
Cireli, Emel
Cirak, Ali
Tatar, Dursun
Gayaf, Mine
Karaoglanoglu, Selen
Aydin, Yener
Eroglu, Atilla
Olcar, Yildiz
Yildirim, Berna
Gursoy, Bengul
Yilmaz, Deniz
Niksarlioglu, Elif
Eren, Ramazan
Erdem, Aysegul
Tor, Muge Meltem
Fakili, Fusun
Colak, Mustafa
Ercelik, Merve
Tabaru, Ali
Ediboglu, Ozlem
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Objective: To identify the clinical characteristics and outcomes of hospital-acquired SARS-CoV-2 infection during the vaccination period nationwide in Turkey. Methods: COVID-19 patients followed in the pandemic services across Turkey between January 1, 2021, and March 31, 2022 were investigated retrospectively. Nosocomial COVID-19 was defined as a patient neither diagnosed with COVID-19 nor suspected COVID-19 at the hospital admission and was confirmed COVID-19 >= 5 days after hospital admission. The primary outcome of this study was in-hospital mortality; demographic features and vaccination status was compared between survivors and non survivors. Results: During the study period, 15 573 COVID-19 patients were followed in 18 centers and 543 (3.5%) patients were nosocomial COVID-19. Most patients with nosocomial COVID-19 (80.4%) were transferred from medical wards. 162 (29.8%) of the patients with nosocomial COVID-19 admitted to the intensive care unit due to disease severity and 138 (25.4%) of the patients died during hospital stay. Advanced age (>= 65 years) and number of comorbid diseases (>= 2) was found to be associated with mortality in nosocomial COVID-19 (OR 1.74, 95% CI 1.11-2.74 and OR 1.60, 95% CI 1.02-2.56, respectively). Vaccination was associated with survival in nosocomial COVID-19 (OR 0.25, 95% CI0.16-0.38). Conclusions: Patients with nosocomial COVID-19 had increased admission to intensive care units and higher mortality rate. Vaccination can decrease the in-hospital mortality rate.
Bağlantı
https://journals.lww.com/aptm/fulltext/2023/16080/clinical_characteristics_and_outcomes_of.3.aspxhttp://hdl.handle.net/11727/11942