dc.contributor.author | Yılmaz, M. | |
dc.contributor.author | Altın, C. | |
dc.contributor.author | Özyıldız, A. | |
dc.contributor.author | Müderrisoğlu, H. | |
dc.date.accessioned | 2019-06-30T21:02:14Z | |
dc.date.available | 2019-06-30T21:02:14Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 13084488 | |
dc.identifier.uri | https://www.journalagent.com/tkd/pdfs/TKDA_45_7_599_605.pdf | |
dc.identifier.uri | http://hdl.handle.net/11727/3766 | |
dc.description.abstract | OBJECTIVE: The aim of this study was to investigate the relationship between oxidative/antioxidative stress markers and the diagnosis and complexity of coronary artery disease (CAD) in patients with stable CAD.
METHODS: A total of 145 patients were enrolled in the study. Based on coronary angiography results, the patients were categorized into 2 groups: those without CAD (Group 1) and those with CAD (Group 2). The patients in Group 2 were also categorized into low score and moderate/high score groups according to their SYNTAX score. The serum malondialdehyde (MDA) and total antioxidant capacity (TAOC) levels of Group 1 and Group 2 were compared. Finally, MDA and TAOC levels were compared between the moderate/high-risk and low-risk groups formed according to SYNTAX score.
RESULTS: There was a significant difference with respect to both serum TAOC and MDA levels between Group 1 and Group 2 (p=0.036 and p=0.029, respectively). The groups with a SYNTAX score 1-22 and with a SYNTAX score >22 were not significantly different with respect to serum TAOC or MDA level (p=0.582 and p=0.85, respectively).
CONCLUSION: The serum MDA level was significantly higher and the TAOC level was significantly lower in patients with stable CAD compared to those without; however, these molecule levels failed to predict disease complexity in patients with stable CAD. | en_US |
dc.language.iso | eng | en_US |
dc.relation.isversionof | 10.5543/tkda.2017.80733 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | antioxidant | en_US |
dc.subject | biological marker | en_US |
dc.subject | malonaldehyde | en_US |
dc.title | Are oxidative stress markers helpful for diagnosing the disease and determining its complexity or extent in patients with stable coronary artery disease? | en_US |
dc.type | article | en_US |
dc.relation.journal | Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir | en_US |
dc.identifier.volume | 45 | en_US |
dc.identifier.issue | 7 | en_US |
dc.identifier.startpage | 599 | en_US |
dc.identifier.endpage | 605 | en_US |
dc.identifier.wos | 000418480800005 | en_US |
dc.identifier.scopus | 2-s2.0-85049059483 | en_US |
dc.contributor.pubmedID | 28990940 | en_US |
dc.contributor.orcID | 0000-0002-2557-9579 | en_US |
dc.contributor.orcID | 0000-0002-9635-6313 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | en_US |
dc.contributor.researcherID | S-6973-2016 | en_US |
dc.contributor.researcherID | AAG-8233-2020 | en_US |