Basit öğe kaydını göster

dc.contributor.authorOzcelikay, G.
dc.contributor.authorKaya, S., I
dc.contributor.authorOzkan, E.
dc.contributor.authorCetinkaya, A.
dc.contributor.authorNemutlu, E.
dc.contributor.authorKir, S.
dc.contributor.authorOzkan, S.A.
dc.date.accessioned2022-12-14T12:35:45Z
dc.date.available2022-12-14T12:35:45Z
dc.date.issued2022
dc.identifier.issn0165-9936en_US
dc.identifier.urihttps://reader.elsevier.com/reader/sd/pii/S0165993621003101?token=1297669476378BBF56AA1C7DC6EFD562469EFD3F46CBE1D85D34D3DB42F4E7615393B9BAA9E17068A188117BC2D25CDF&originRegion=eu-west-1&originCreation=20221214123430
dc.identifier.urihttp://hdl.handle.net/11727/8296
dc.description.abstractIn recent years, metabolomics, identification and profiling of metabolites, have gained broad interest compared to other omics technologies and are progressively being utilized for biomarker discoveries. Therefore, the application of metabolomics in different fields are increasing day by day because of its high throughput results. However, the application of metabolomics requires state-of-the-art analytical approaches for the analysis. The complexity and limited availability of these instruments are restricting parameters for applying metabolomics studies in routine analysis. This problem may be overcome with molecularly imprinted polymer (MIP)-based electro sensors since they have high selectivity, sensitivity, easy applicability, portability, and low cost. This is the final step before developing end point-of-care tests (POCT), which patients can easily apply. MIP sensors will have more applications in the targeted metabolomics analysis to develop POCT systems. This review analyzes various metabolites using MIP-based electrochemical methods for their potential usage as POCT and biomarker research based on targeted metabolomics analysis requirements. The future applications for the sensitive assay of metabolites in medicine and clinical trials are also discussed. (C) 2021 Elsevier B.V. All rights reserved.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1016/j.trac.2021.116487en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMetabolomicsen_US
dc.subjectMolecularly imprinted polymeren_US
dc.subjectNanomaterialen_US
dc.subjectBiosensoren_US
dc.subjectAnalysisen_US
dc.titleSensor-based MIP technologies for targeted metabolomics analysisen_US
dc.typearticleen_US
dc.relation.journalTRAC-TRENDS IN ANALYTICAL CHEMISTRYen_US
dc.identifier.volume146en_US
dc.identifier.wos000806643600009en_US
dc.identifier.scopus2-s2.0-85120414315en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


Bu öğenin dosyaları:

Thumbnail

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster