Basit öğe kaydını göster

dc.contributor.authorGur Gungor, Sirel
dc.contributor.authorGokgoz, Gulsah
dc.contributor.authorSarigul Sezenoz, Almila
dc.contributor.authorOzturk, Caner Caner
dc.contributor.authorAkman, Ahmet
dc.date.accessioned2022-09-16T12:44:22Z
dc.date.available2022-09-16T12:44:22Z
dc.date.issued2021
dc.identifier.issn1057-0829en_US
dc.identifier.urihttps://journals.lww.com/glaucomajournal/Fulltext/2021/01000/Peripapillary_and_Macular_Vessel_Density.13.aspx
dc.identifier.urihttp://hdl.handle.net/11727/7816
dc.description.abstractPrecis: Although peripapillary retinal nerve fiber layer thickness (RNFLTs) and vessel density (VD) values were similar to healthy group, eyes with exfoliation syndrome had significantly lower superficial macular VDs and minimum ganglion cell analysis values. Purpose: To compare peripapillary and macular perfused capillary densities with optical coherence tomography angiography (OCT-A) between patients with eyes having exfoliation syndrome (XFS) and normal age-matched healthy controls. Patients and Methods: This cross-sectional study included patients diagnosed with XFS from December 2017 to January 2020 at the Glaucoma Department. Peripapillary and parafoveal superficial VDs were obtained using OCT-A. The RNFLTs and ganglion cell analysis values were compared. Results: Thirty-nine eyes of 39 XFS patients (26 women; mean age, 69.0 +/- 8.1 y) and 39 eyes of 39 healthy patients (25 women; mean age, 68.0 +/- 8.6 y) were enrolled. There were no statistically significant differences in sex or age distribution, central corneal thickness measurements, refractive errors, or intraocular pressures between both groups (all P>0.05). There were no statistically significant differences in the peripapillary VD or peripapillary RNFLT between XFS eyes and healthy eyes (P>0.05 for all). In the macular region, most superficial VD parameters were significantly reduced in the XFS group (P=0.02 for parafoveal VD, P=0.04 for both hemifields). While the average ganglion cell and internal plexiform layer (GCL+IPL) values were similar between groups (P=0.19), the minimum GCL+IPL value was lower in the XFS group than in the healthy group (P=0.03). Conclusion: Although structural test results, especially peripapillary RNFLT and mean GCL+IPL, were similar between the healthy and XFS groups, macular VD values were lower in XFS eyes. Our findings implicate microvascular damage can be the mechanism underlying XFS-related changes and indicate that it precedes significant structural damage.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1097/IJG.0000000000001685en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectoptical coherence tomography angiographyen_US
dc.subjectexfoliation syndromeen_US
dc.subjectretinal nerve fiber layer thicknessesen_US
dc.subjectvessel densityen_US
dc.titlePeripapillary and Macular Vessel Density Measurement With Optical Coherence Tomography Angiography in Exfoliation Syndromeen_US
dc.typearticleen_US
dc.relation.journalJOURNAL OF GLAUCOMAen_US
dc.identifier.volume30en_US
dc.identifier.issue1en_US
dc.identifier.startpage71en_US
dc.identifier.endpage77en_US
dc.identifier.wos000610964500023en_US
dc.identifier.scopus2-s2.0-85099072543en_US
dc.contributor.pubmedID32976289en_US
dc.contributor.orcID0000-0002-4837-7937en_US
dc.contributor.orcID0000-0002-7030-5454en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.contributor.researcherIDAAY-7932-2021en_US
dc.contributor.researcherIDAAJ-4860-2021en_US


Bu öğenin dosyaları:

Thumbnail

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster