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dc.contributor.authorSar, C.
dc.contributor.authorAkdeniz, S. S.
dc.contributor.authorOzcirpici, A. Arman
dc.contributor.authorHelvacioglu, F.
dc.contributor.authorBacanli, D.
dc.date.accessioned2020-10-23T12:25:41Z
dc.date.available2020-10-23T12:25:41Z
dc.date.issued2019
dc.identifier.issn0901-5027en_US
dc.identifier.urihttp://hdl.handle.net/11727/4963
dc.description.abstractThe aim of this study was to evaluate the effect of platelet-rich fibrin (PRF) membrane on tooth movement in comparison with shunt control and piezoelectric surgery. Sixteen White Vienna rabbits were included in the study and divided into two groups. Reciprocal forces (20 g) were applied on the maxillary incisors by an orthodontic appliance. In group 1, PRF membrane was placed subperiosteally on the distal alveolar bone surface of the right central incisors and the left side was kept as control. In group 2, piezo-incisions 3 mm in depth were performed and combined with PRF membrane on the distal alveolar bone surface of the right central incisors, while the left side was kept as control. All rabbits were euthanized on day 21 and bilateral alveolar bone segments from the distal regions were removed for histological evaluation. Isolated PRF membrane application increased the blood vessel (8.3 +/- 1.0; P= 0.026), osteoblast (6 +/- 0.8; P= 0.027), and osteoclast (2.3 +/- 0.8; P= 0.026) counts significantly compared to shunt control. Combined application of PRF membrane +piezo-incision increased the blood vessel (15.3 +/- 0.8; P= 0.027), osteoblast (9.8 +/- 1.4; P= 0.026), and osteoclast (3.3 +/- 0.8; P= 0.024) counts significantly compared to shunt control. The increases in blood vessel count and osteoblast cell count were more evident in the combined application group (both P= 0.002). PRF membrane application significantly increased bone turnover, and the combined application of PRF membrane + piezo-incision was found to be the best method for increasing bone turnover.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1016/j.ijom.2019.04.001en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaccelerated tooth movementen_US
dc.subjectplatelet-rich fibrinen_US
dc.subjectPRFen_US
dc.subjectPRF membraneen_US
dc.subjectpiezoelectric surgeryen_US
dc.subjectpiezo-incisionen_US
dc.titleHistological evaluation of combined platelet-rich fibrin membrane and piezo-incision application in orthodontic tooth movementen_US
dc.typearticleen_US
dc.relation.journalINTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERYen_US
dc.identifier.volume48en_US
dc.identifier.issue10en_US
dc.identifier.startpage1380en_US
dc.identifier.endpage1385en_US
dc.identifier.wos000491302500017en_US
dc.identifier.scopus2-s2.0-85064898590en_US
dc.contributor.pubmedID31053517en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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