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dc.contributor.authorYuce, Ozge
dc.contributor.authorBayrakci, Umut Selda
dc.contributor.authorGulleroglu, Kaan
dc.contributor.authorBaskin, Esra
dc.date.accessioned2019-08-02T13:04:32Z
dc.date.available2019-08-02T13:04:32Z
dc.date.issued2016
dc.identifier.issn0886-022X
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.3109/0886022X.2016.1164064
dc.identifier.urihttp://hdl.handle.net/11727/3802
dc.description.abstractIntroduction: To investigate autonomic nervous system function in enuretic children by performing ambulatory blood pressure monitor (ABPM) for 24h. Methods: Twenty-eight children ranging in age from 6 to 15 years with primary nocturnal enuresis and 27 age-matched healthy controls were enrolled and they get 24h ABPM. Hypertension was defined as standard deviation score (SDS)>1.64 (i.e., >95th percentile) adjusted for gender and height. Urinalysis, urine electrolyte levels, urinary culture, and urinary system ultrasound were carried out in all children. They have also requested to have a diary about daily fluid intake and urine volume. Results: Although the mean 24-h and daytime diastolic blood pressure (BP) did not differ between the groups, systolic BP (SBP) was significantly higher in enuretic children (p<0.05). The mean night-time SBP, DBP values, SDS and BP loads were found to be significantly higher than those in the controls (p<0.01). A lack of nocturnal decrease was more prevalent in the enuretic children compared with the control subjects, the difference was statistically significant for DBP but not for SBP. Patients with elevated night-time BP load was found to have higher frequency of urinary incontinence per week as well as per night when compared with enuretic children with normal night-time BP load (r=0.72, r=0.69, p<0.01, respectively). Conclusion: Subtle abnormalities of circadian BP regulation in enuretic children indicated by a selective elevation of nocturnal SBP, DBP, and MAP, and attenuated nocturnal dipping may reflect sympathetic hyper activation and its possible role in pathogenesis of enuresis.en_US
dc.language.isoengen_US
dc.relation.isversionof10.3109/0886022X.2016.1164064en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAmbulatory blood pressure monitoren_US
dc.subjectautonomic nervous system activityen_US
dc.subjectblood pressureen_US
dc.subjectenuresis nocturnaen_US
dc.subjecthypertensionen_US
dc.titleAbnormal circadian blood pressure regulation in children with nocturnal enuresisen_US
dc.typearticleen_US
dc.relation.journalRENAL FAILUREen_US
dc.identifier.volume38en_US
dc.identifier.issue6en_US
dc.identifier.startpage899en_US
dc.identifier.endpage905en_US
dc.identifier.wos000379778100007en_US
dc.identifier.scopus2-s2.0-84964057122en_US
dc.contributor.pubmedID27056252en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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