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dc.contributor.authorTuncali, Bahattin
dc.contributor.authorAraz, Coskun
dc.contributor.authorCelebi, Arzu
dc.date.accessioned2019-05-06T08:15:17Z
dc.date.available2019-05-06T08:15:17Z
dc.date.issued2018
dc.identifier.issn1300-4948
dc.identifier.urihttp://www.turkjgastroenterol.org/sayilar/307/buyuk/335-41.pdf
dc.identifier.urihttp://hdl.handle.net/11727/3184
dc.description.abstractBackground/Aims: it is unclear whether patients with irritable bowel syndrome (IBS) require a high dose of sedatives during colonoscopy. In this study, we investigated the pre-procedural anxiety levels, sedative consumption, procedure times, complications, and patient's satisfaction between patients with IBS and controls for ambulatory colonoscopy under sedation. Materials and Methods: Rome III criteria were used in the diagnosis of IBS. Anxiety levels were measured using Spielberger's State-Trait Anxiety Inventory (STAI) and Beck Anxiety Inventory (BA/). Patients received a fixed dose of midazolam (0.02 mg/kg), fentanyl (1 mu g/kg), ketamine (0.3 mg/kg), and incremental doses of propofol under sedation protocol. Demographic data, heart rate, blood pressure, and oxygen saturation were measured. Procedure times, recovery and discharge times, drug doses used, complications associated with the sedation, and patient's satisfaction scores were also recorded. Results: The mean Trait (p=0.015), State (p=0.029), Beck anxiety scores (p=0.018), the incidence of disruptive movements (p=0.044), and the amount of propofol (p=0.024) used were significantly higher in patients with IBS. There was a decline in mean systolic blood pressure at the 6th minute in patients with IBS (p=0.026). No association was found between the sedative requirement and the anxiety scores. Conclusion: Patients with IBS who underwent elective colonoscopy procedures expressed higher pre-procedural anxiety scores, required more propofol consumption, and experienced more disruptive movements compared with controls. On the contrary, the increased propofol consumption was not associated with the increased pre-procedural anxiety scores.en_US
dc.language.isoengen_US
dc.relation.isversionof10.5152/tjg.2018.17590en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectColonoscopyen_US
dc.subjectIrritable bowel syndromeen_US
dc.subjectSedationen_US
dc.subjectAnxietyen_US
dc.titleAmbulatory colonoscopy under sedoanalgesia in adult patients with and without irritable bowel syndrome: A prospective, cross-sectional, and double-blind comparisonen_US
dc.typearticleen_US
dc.relation.journalTURKISH JOURNAL OF GASTROENTEROLOGYen_US
dc.identifier.volume29en_US
dc.identifier.issue3en_US
dc.identifier.startpage335en_US
dc.identifier.endpage341en_US
dc.identifier.wos000440300700010en_US
dc.identifier.scopus2-s2.0-85050499570en_US
dc.contributor.pubmedID29755018en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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