Basit öğe kaydını göster

dc.contributor.authorHaydedeoglu, Filiz Eksi
dc.contributor.authorBagir, Gulay Simsek
dc.contributor.authorTorun, Nese
dc.contributor.authorKocer, Emra H.
dc.contributor.authorReyhan, Mehmet
dc.contributor.authorErtorer, Melek Eda
dc.date.accessioned2019-05-04T13:48:36Z
dc.date.available2019-05-04T13:48:36Z
dc.date.issued2018
dc.identifier.issn2359-3997
dc.identifier.urihttp://www.scielo.br/scielo.php?pid=S2359-39972018000400460&script=sci_arttext
dc.identifier.urihttp://hdl.handle.net/11727/3136
dc.description.abstractObjective: Detection rate of thyroid nodules is increasing with the use of new imaging modalities, especially in screening for malignancies. Positron emission tomography/computed tomography (PET/CT)-positive thyroid nodules should be differentiated for malignancy to avoid unnecessary operations and further follow-up. Most trials evaluate the role of SUVmax, but there is no definitive information about the utility of Hounsfield unit (HU) values for prediction of malignancy. This study aimed to evaluate the HU values beside SUVmax for detecting malignancy risk of PET/CT-positive thyroid nodules. Subjects and methods: Results of 98 cancer patients who had fine needle aspiration biopsy (FNAB) for thyroid nodules detected on PET/CT between January 2011 and December 2015 were assessed. The FNABs and surgical pathological results were recorded. Results: FNABs revealed benign results in 32 patients (32.7%), malignant in 18 (18.4%), non-diagnostic in 20 (20.4%), and indeterminate in 28 (28.5%). Twenty-four patients underwent thyroidectomy. The mean HU values were not significantly different in benign and malignant nodules (p = 0.73). However, the mean SUVmax was significantly higher (p < 0.001) in malignant ones. Area under curve (AUC) was 0.824 for SUVmax; the cut-off value was over 5.55 (p < 0.001), with 80% sensitivity, 84.5% specificity. Conclusions: Our current study demonstrated that HU value does not add any additional valuable information for discriminating between malignant and benign thyroid nodules. We also defined a SUVmax cut-off value of 5.55 for malignant potential of thyroid nodules detected on PET/CT.en_US
dc.language.isoengen_US
dc.relation.isversionof10.20945/2359-3997000000063en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThyroid nodulesen_US
dc.subjectMalignancyen_US
dc.subjectPET-CTen_US
dc.subjectSUVmaxen_US
dc.subjectHounsfield Uniten_US
dc.titleHounsfield unit value has null effect on thyroid nodules at F-18-FDG PET/CT scansen_US
dc.typearticleen_US
dc.relation.journalARCHIVES OF ENDOCRINOLOGY METABOLISMen_US
dc.identifier.volume62en_US
dc.identifier.issue4en_US
dc.identifier.startpage460en_US
dc.identifier.endpage465en_US
dc.identifier.wos000446605900011en_US
dc.contributor.pubmedID30304111en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


Bu öğenin dosyaları:

Thumbnail

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster