• Türkçe
    • English
  • English 
    • Türkçe
    • English
  • Login
View Item 
  •   DSpace Home
  • Fakülteler / Faculties
  • Tıp Fakültesi / Faculty of Medicine
  • View Item
  •   DSpace Home
  • Fakülteler / Faculties
  • Tıp Fakültesi / Faculty of Medicine
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Effects of HCV-RNA positivity on serum IL-1 beta levels in chronic hemodialysis patients

Thumbnail
View/Open
uvt_14386.pdf (76.35Kb)
Date
2001
Author
Yücel, Ayşegül
Köseoğlu, Hamide
Yücel, Ahmet Eftal
Özdemir, Nurhan
Haberal, Mehmet
Metadata
Show full item record
Abstract
Hepatitis C virüs (HCV) positivity and inflammatory cytokines such as interleukin(IL)-} beta, tumor necrosis factor-alpha and IL-6 secreted by activated macrophages are known to be important morbidity factors in chronic hemodialysis (HD) patients. in this preliminary stııdy, we aimed to compare serum IL-1 beta levels of 20 HCV-RNA-positive and 23 HCV-RNA-negative chronic HD patients. Methods: HCV-RNA-positivity and serum IL-1 beta levels were studied using nested reverse transcriptase-polymerase chain reaction and ELISA methods, respectively. Results: We could detect no statistically signifıcant difference between serum IL-1 beta levels in HCV-RNA-positive and HCV-RNA-negative groups (p>0.05). Conclusion: To our knowledge, this is the fırst study to examine the relationship between serum IL-1 beta level and HCV infection in HD patients. We had expected the level of IL-1 beta to be higher in HCV-RNA-positive group, and believe that the blood-dialyzer interaction strongly activated mononuclear cells, thus generating elevated levels of IL-1 beta in both groups. This could explain why HCV infection apparently did not affect serum IL-1 beta levels.
URI
http://uvt.ulakbim.gov.tr/uvt/index.php?cwid=9&vtadi=TPRJ%2CTTAR%2CTTIP&ano=14386_81d1dc34d5437b514b4e14ce33805daa
http://hdl.handle.net/11727/2041
Collections
  • Tıp Fakültesi / Faculty of Medicine [2109]

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV
 

 

  • Politika

Politika
Kullanıcı Rehberi
Başkent Üniversitesi Kütüphanesi
Başkent Üniversitesi

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsxmlui.ArtifactBrowser.Navigation.browse_typexmlui.ArtifactBrowser.Navigation.browse_languagexmlui.ArtifactBrowser.Navigation.browse_publicationcategoryThis CollectionBy Issue DateAuthorsTitlesSubjectsxmlui.ArtifactBrowser.Navigation.browse_typexmlui.ArtifactBrowser.Navigation.browse_languagexmlui.ArtifactBrowser.Navigation.browse_publicationcategory

My Account

LoginRegister

Statistics

View Usage Statistics

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV