Association of Disease Activity with Serum and Tear IL-2 Levels in Behc, et Disease
Tarih
2016Yazar
Turkcuoglu, Peykan
Arat, Yonca Ozkan
Kan, Emrah
Kan, Elif Kilic
Chaudhry, Imtiaz A.
Koca, Suleyman
Celiker, Ulku
Ilhan, Nevin
Üst veri
Tüm öğe kaydını gösterÖzet
Purpose: To investigate the association of Behcet disease activity with serum and tear interleukin-2 levels.
Methods: The study was designed as a prospective case control study. The study population consisted of 45 patients with Behcet disease and 24 age and sex-matched healthy participants. Behcet disease patients were classified as active (24 patients) or inactive (21 patients) according to disease activity. Serum and tear interleukin-2 levels were determined using the enzyme-linked immunosorbent assay method.
Results: The mean serum and tear interleukin-2 levels of the active disease, inactive disease, and control groups were 17.04 +/- 5.02 and 32.61 +/- 16.53 pg/mL; 15.20 +/- 4.68 and 29.61 +/- 8.30 pg/mL; and 14.22 +/- 4.18 and 28.89 +/- 8.73 pg/mL, respectively. There was no statistically significant difference between the groups with respect to all measured data.
Conclusions: There was no significant difference in serum or tear IL-2 levels between Behcet patients and controls; there was no association of disease activity with serum and tear IL-2 levels.