Yazar "0000-0002-1872-028X" için listeleme
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Antibacterial Resistance in Lower Respiratory Tract Bacterial Pathogens: A Multicenter Analysis from Turkey
Guclu, Aylin Uskudar; Kocak, Aylin Altay; Ok, Mehtap Akcil; Tutluoglu, Bulent; Basustaoglu, Ahmet (2021)Introduction: This study aimed to evaluate the etiology of lower respiratory tract infections (LRTIs) and their antibiotic resistance. Methodology: Bacterial culture results of LRT samples from 17 hospitals between ... -
Antibacterial, Antifungal and Antibiofilm Activity of Methylglyoxal: A Phytochemical from Manuka Honey Metilglioksalin Antibakteriyel, Antifungal ve Antibiyofilm Aktivitesi: Manuka Balindan Bir Fitokimyasal
Uskudar-Guclu, Aylin; Simsek, Derya; Ata-Vural, Ilgin; Unlu, Sezin; Basustaoglu, Ahmet (2021)Introduction: Honey has been known for its ability to promote wound healing for a long time. It is utilized for several skin and soft tissue infections caused by a wide range of microorganisms due to its antimicrobial ... -
Comparative in Vitro Activities of Omadacycline, Eravacycline and Tigecycline Against Non-ESBL- Producing ESBL- Producing and Carbapenem- Resistant Isolates of K. Pneumoniae
Mirza, Hasan Cenk; Guclu, Aylin Uskudar; Ceviz, Gizem Ince; Basustaoglu, Ahmet (2022)Introduction. Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae and carbapenem-resistant Enterobacte-riaceae are characterized by the World Health Organization as pathogens for which new antibiotics are ... -
Comparison of in vitro activities of plazomicin and other aminoglycosides against clinical isolates of Klebsiella pneumoniae and Escherichia coli
Ince, Gizem; Mirza, Hasan Cenk; Guclu, Aylin Uskudar; Gumus, Hale; Erol, Cigdem; Basustaoglu, Ahmet (2021)Objectives: To compare the in vitro activity of plazomicin and two older aminoglycosides (gentamicin and amikacin) against 180 isolates of Escherichia coli and Klebsiella pneumoniae, including subsets of 60 non-ESBL-producing, ... -
Electrospinning of linezolid loaded PLGA nanofibers: effect of solvents on its spinnability, drug delivery, mechanical properties, and antibacterial activities
Eren Boncu, Tugba; Ozdemir, Nurten; Uskudar Guclu, Aylin (2020)Objective: The choice of a desirable solvent/solvent system is fundamental for optimization of electrospinning by altering the rheological and electrostatic properties of the polymer solutions. Methods: The effects of the ... -
Genetic Diversity of OXA-like Genes in Multidrug-Resistant Acinetobacter baumannii Strains from ICUs
Guclu, Aylin; Gozen, Ayse G. (2020)Background: This study aimed to investigate the genetic diversity of OXA-51-like, OXA-23-like, OXA-24, and OXA-58-like genes and the role of beta-lactamases in carbapenem resistance among multidrug resistant Acinetobacter ... -
In vitro activity of ceftolozane-tazobactam and ceftazidime-avibactam against clinical isolates of meropenem-non-susceptible Pseudomonas aeruginosa: A two-centre study
Mirza, Hasan Cenk; Hortac, Elvan; Kocak, Aylin Altay; Demirkaya, M. Hamiyet; Yayla, Buket; Guclu, Aylin Uskudar; Bustaoglu, Ahmet (2020)Objectives: This study aimed to compare the activity of ceftazidime-avibactam (C/A), ceftolozane-tazobactam (C/T) and three anti-pseudomonal beta-lactams (piperacillin-tazobactam, ceftazidime and cefepime) against a ... -
In vitro and in vivo evaluation of linezolid loaded electrospun PLGA and PLGA/PCL fiber mats for prophylaxis and treatment of MRSA induced prosthetic infections
Boncu, Tugba Eren; Guclu, Aylin Uskudar; Catma, Mehmet Faruk; Savaser, Ayhan; Gokce, Aysun; Ozdemir, Nurten (2020)In this study, it was aimed to formulate linezolid loaded electrospun PLGA and PCL fiber mats doing controlled drug release, to be used in the treatment and prophylaxis of the prosthesis related infections. The effect of ... -
An Investigation into Bacterial Bloodstream Infections and Antibiotic Resistance Profiles in a Tertiary Hospital for a Ten-Year Period
Mataj, Valbona; Guney, Mustafa; Sig, Ali Korhan; Uskudar-Guclu, Aylin; Albay, Ali; Bedir, Orhan; Baysallar, Mehmet (2020)Background: Bloodstream infections are one of the major causes of healthcare-associated morbidity and mortality. The present study aims to investigate the prevalence of the microorganisms isolated from blood cultures and ... -
Predominant Mutations of SARS-CoV-2: Their Geographical Distribution and Potential Consequences
Unlu, Sezin; Uskudar Guclu, Aylin; Basustaoglu, Ahmet (2021)Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) emerged in late December 2019 in Wuhan, China. More than 83 million people have been infected, and more than 1.8 million people have died, as reported to the ... -
Prevalence and Quantity of Parvovirus B19 DNA Among Blood Donors from a Regional Blood Center in Turkey
Guclu, Aylin Uskudar; Yilmaz, Soner; Baysallar, Mehmet; Avci, Ismail Yasar (2020)Objective: Parvovirus B19 causes a range of diseases and morbidity in humans and is transmissible by transfusion of blood, blood components and plasma derivatives. The objective of the study was to investigate the prevalence ... -
Prevalence of CMV DNA in Blood Donors in a Regional Blood Center in Turkey
Uskudar Guclu, Aylin; Yilmaz, Soner; Baysallar, Mehmet; Ayci, Ismail Yasar (2022)Cytomegalovirus (CMV) infections with a high seroprevalence rate in adults are often asymptomatic or mild. The current prevalence of CMV DNA in Turkey is not known. This study aimed to find out the prevalence and quantity ...